Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038936 | 0.87 | TDP1 (0.44) | TDP1PLA2G2ABLMKEAP1NFE2L2 | |
| SCHEMBL342249 | 0.81 | ALDH1A1 (0.44) | TDP1BLMKEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL13645018 | 0.78 | CA2 (0.46) | TDP1PLA2G2ABLMALDH1A1LMNA | |
| SCHEMBL202173 | 0.78 | TDP1 (0.50) | TDP1PLA2G2ABLMSMN1; SMN2ALDH1A1 | |
| SCHEMBL9974573 | 0.77 | KEAP1 (0.56) | KEAP1NFE2L2SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL341751 | 0.77 | TDP1 (0.50) | TDP1PLA2G2ABLMKEAP1NFE2L2 | |
| SCHEMBL18360374 | 0.77 | POLB (0.44) | TDP1PLA2G2ABLMSMN1; SMN2GMNN | |
| SCHEMBL4142849 | 0.77 | TDP1 (0.42) | TDP1KEAP1NFE2L2ALDH1A1MAPT | |
| SCHEMBL340532 | 0.77 | MEN1 (0.42) | TDP1KEAP1NFE2L2ALDH1A1MAPT | |
| SCHEMBL13644976 | 0.77 | ALDH1A1 (0.50) | TDP1SMN1; SMN2ALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747704-B1 | Immunoassay element containing a diaryl telluride compound to increase its stability | ORTHO CLINICAL DIAGNOSTICS INC (US) | 2003-12-10 | — | — | EP | disclosed |
| EP-0903583-B1 | Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film immunoassay elements | ORTHO CLINICAL DIAGNOSTICS INC (US) | 2003-11-12 | — | — | EP | disclosed |
| US-5928886-A | SUPPORT HAVING ZONE OF ENZYME LABELED LIGAND OR ENZYME LABELED RECEPTOR, SPREADING ZONE, ZONE OF IMMOBILIZED RECEPTOR OF LIGAND, AND GRAVURE ZONE WITH DIARYL TELLURIDE; INCREASED STORAGE STABILITY | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0903583-A2 | Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film immunoassay elements | Ortho-Clinical Diagnostics, Inc. (US) | 1999-03-24 | — | — | EP | disclosed |
| US-5686254-A | Reduction in first slide bias and improved enzyme stability by the incorporation of diaryl tellurides in thin-film immunoassay elements | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0747704-A2 | Immunoassay element containing a diaryl telluride compound to increase its stability | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1996-12-11 | — | — | EP | disclosed |