Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.39 |
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423193 | 0.79 | KMT2A (0.43) | MEN1KMT2ADDB1CRBN | |
| SCHEMBL18722714 | 0.77 | CA1 (0.40) | CA1CA2CA7CA9LRRK2 | |
| SCHEMBL30122758 | 0.74 | MAOA (0.45) | LRRK2MEN1KMT2A | |
| SCHEMBL17993494 | 0.71 | LRRK2 (0.54) | CA1CA2CA7CA9LRRK2 | |
| SCHEMBL13284385 | 0.71 | LMNA (0.61) | MEN1KMT2ACCNE1CDK2CCNE2 | |
| SCHEMBL28035946 | 0.70 | PGR (0.44) | — | |
| SCHEMBL5063224 | 0.70 | NTRK1 (0.52) | CA1CA2LRRK2FLT3MEN1 | |
| SCHEMBL2615325 | 0.69 | LMNA (0.73) | MEN1KMT2ACCNE1CDK2CCNE2 | |
| SCHEMBL1185886 | 0.69 | ALDH1A1 (0.49) | LRRK2FLT3MEN1KMT2AACHE | |
| SCHEMBL13284429 | 0.68 | LMNA (0.62) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |