Acitazanolast

Acitazanolast

SCHEMBL342549

O=C(O)C(=O)Nc1cccc(-c2nnn[nH]2)c1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.54
PTPN11 Q06124 3/20 0.44
PTPN1 P18031 1/20 0.44
MGLL Q99685 1/20 0.43
MAPT P10636 3/20 0.42
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
COMT P21964 1/20 0.41
MMP8 P22894 1/20 0.41
MMP13 P45452 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
TSHR P16473 1/20 0.40
KDM4E B2RXH2 4/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
POLB P06746 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acitazanolast SCHEMBL3116621 0.99 GPR35 (0.53) GPR35PTPN11PTPN1MGLLMAPT
SCHEMBL9314587 0.89 MGLL (0.45) MGLLMAPTMMP2MMP9COMT
SCHEMBL22167182 0.87 MGLL (0.54) MGLLMAPTMEN1KMT2AALDH1A1
SCHEMBL6694019 0.84 MAPT (0.59) MAPTSMN1; SMN2NPC1RAB9ATSHR
SCHEMBL9573406 0.84 MAPT (0.43) MGLLMAPTMMP2MMP9COMT
SCHEMBL31680549 0.82 MMP2 (0.54) MAPTMMP2MMP9COMTMMP8
SCHEMBL950001 0.81 CYP3A4 (0.60) MAPTSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL4532779 0.79 KDM4E (0.53) MGLLMAPTSMN1; SMN2NPC1RAB9A
SCHEMBL23796628 0.79 LMNA (0.41) MAPTMMP2MMP9COMTMMP8
Tazanolast SCHEMBL28495 0.79 HPGD (0.45) MAPTSMN1; SMN2NPC1RAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 630 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250009940-A1 ANTIMICROBIAL WRAPS FOR MEDICAL IMPLANTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-01-09 US claimed
EP-4433107-A1 ANTIMICROBIAL WRAPS FOR MEDICAL IMPLANTS Board of Regents, The University of Texas System (US) 2024-09-25 EP claimed
US-20240033124-A1 DRUG DELIVERY CONTACT LENS AND OPHTHALMIC PHARMACEUTICAL COMPOSITION DAE WON PHARMACEUTICAL CO., LTD (KR) 2024-02-01 US claimed
EP-4275675-A1 DRUG DELIVERY CONTACT LENS AND OPHTHALMIC PHARMACEUTICAL COMPOSITION Dae Won Pharmaceutical Co., Ltd. (KR) 2023-11-15 EP claimed
WO-2023091998-A1 ANTIMICROBIAL WRAPS FOR MEDICAL IMPLANTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-05-25 WO claimed
WO-2023069028-A1 A PROCESS FOR THE PREPARATION OF DRY POWDER COMPOSITIONS FOR INHALATION Arven Ilac Sanayi Ve Ticaret Anonim Sirketi (TR) 2023-04-27 WO claimed
WO-2022149914-A1 DRUG DELIVERY CONTACT LENS AND OPHTHALMIC PHARMACEUTICAL COMPOSITION 대원제약 주식회사 2022-07-14 WO claimed
US-20210178023-A1 ANTIMICROBIAL WRAPS FOR MEDICAL IMPLANTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-06-17 US claimed
EP-2913062-B1 THERAPEUTIC OR PROPHYLACTIC AGENT FOR RETINOPATHY OF PREMATURITY AND METHOD OF TESTING FOR RETINOPATHY OF PREMATURITY JAPAN INNOVATIVE THERAPEUTICS INC (JP) 2019-05-08 EP claimed
CN-109718376-A It releives the ophthalmically acceptable product of effect with antiallergic 晶硕光学股份有限公司 2019-05-07 CN claimed
US-20030162828-A1 Use of leukotriene receptor antagonist for treatment of scarring SCHLESINGER FAMILY PARTNERS, A HAWAII LIMITED PARTNERSHIP 2003-08-28 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
WO-2003024488-A2 COMBINATION OF A PDE INHIBITOR AND A LEUKOTRIENE RECEPTOR ANTAGONIST ALTANA PHARMA AG (DE) 2003-03-27 WO claimed
US-6224907-B1 Anti-asthma therapy ALZA CORPORATION 2001-05-01 US claimed
EP-0694310-B1 REVERSIBLE, THERMALLY GELLING WATER-BASE MEDICINAL COMPOSITION WAKAMOTO PHARMA CO LTD (JP) 2000-02-16 EP claimed
CN-1048393-C Aqueous drug composition having property of reversible thermosetting gelation WAKAMOTO PHARMA CO LTD (JP) 2000-01-19 CN claimed
US-5693337-A OIL IN WATER EMULSION CONTAINING DRUG, LECITHIN, CITRIC ACID, AND METHIONINE, PHENYLALANINE, SERINE, AND/OR HISTIDINE; SYNERGISTIC, STORAGE STABILITY WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) 1997-12-02 US claimed
EP-0700678-A1 Stable lipid emulsion Wakamoto Pharmaceutical Co., Ltd. (JP) 1996-03-13 EP claimed
EP-0481118-B1 A method for producing butyl 3'-(1H-tetrazol-5-yl) oxanilate WAKAMOTO PHARMA CO LTD (JP) 1995-08-02 EP claimed
CN-1097593-A Aqueous drug composition having property of reversible thermosetting gelation WAKAMOTO PHARMA CO LTD (JP) 1995-01-25 CN claimed