Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 10/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22639045 | 0.89 | THRB (0.38) | TSHRFDPSTHRBGGPS1FAAH | |
| SCHEMBL11770459 | 0.89 | TSHR (0.38) | TSHRFDPSSMPD1THRBGGPS1 | |
| SCHEMBL10471420 | 0.87 | TSHR (0.33) | TSHRFDPSSMPD1THRBGGPS1 | |
| SCHEMBL27430264 | 0.80 | THRB (0.38) | TSHRALDH1A1THRBGGPS1FAAH | |
| SCHEMBL26974728 | 0.80 | THRB (0.38) | TSHRALDH1A1THRBGGPS1FAAH | |
| SCHEMBL7692436 | 0.80 | TSHR (0.31) | TSHRTHRBGGPS1FAAHCES2 | |
| SCHEMBL9815806 | 0.79 | DNM1 (0.42) | TSHRALDH1A1FDPSSMPD1THRB | |
| SCHEMBL1876114 | 0.79 | LMNA (0.42) | TSHRALDH1A1FDPSSMPD1GGPS1 | |
| SCHEMBL24322432 | 0.78 | THRB (0.33) | TSHRTHRBFAAHCES2 | |
| SCHEMBL6447572 | 0.78 | TSHR (0.38) | TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790897-B2 | Graftable hindered amine light stabilizers | CIBA SPECIALTY CHEMICALS CORP. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090144915-A1 | Graftable hindered amine light stabilizers | MEIER HANS-RUDOLF | 2009-06-11 | — | — | US | disclosed |
| US-7504510-B2 | Graftable hindered amine light stabilizers | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-03-17 | — | — | US | disclosed |
| EP-1592664-B1 | GRAFTABLE HINDERED AMINE LIGHT STABILIZERS | CIBA SC HOLDING AG (CH) | 2006-08-23 | — | — | EP | disclosed |
| US-20060173107-A1 | Graftable hindered amine light stabilizers | CIBA SPECIALTY CHEMICALS CORP. | 2006-08-03 | — | — | US | disclosed |
| EP-1592664-A1 | GRAFTABLE HINDERED AMINE LIGHT STABILIZERS | Ciba SC Holding AG (CH) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004072035-A1 | GRAFTABLE HINDERED AMINE LIGHT STABILIZERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090144915-A1 | Graftable hindered amine light stabilizers | IDO1, MAOA, AOX1 | TSHR 3638/4885ALDH1A1 29/4885TDP1 280/4885 |
| US-20060173107-A1 | Graftable hindered amine light stabilizers | IDO1, MAOA, TPH1 | TSHR 3853/4885ALDH1A1 50/4885TDP1 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.