SCHEMBL3429032

SCHEMBL3429032

Cc1ccc(O)cc1C=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
TSHR P16473 2/20 0.48
ERN1 O75460 3/20 0.46
ACHE P22303 1/20 0.43
TYR P14679 2/20 0.42
TRIM24 O15164 2/20 0.42
TRIM33 Q9UPN9 2/20 0.42
KDM4E B2RXH2 4/20 0.41
GAA P10253 3/20 0.41
HPGD P15428 3/20 0.41
GLA P06280 2/20 0.41
ALDH5A1 P51649 1/20 0.41
ABAT P80404 1/20 0.41
MAPT P10636 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CA12 O43570 1/20 0.40
LMNA P02545 1/20 0.40
AKR1B1 P15121 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30204286 1.00 ALDH1A1 (0.48) ALDH1A1TSHRERN1ACHETYR
SCHEMBL96219 0.82 ALDH1A1 (0.48) ALDH1A1TSHRERN1TYRTRIM24
SCHEMBL29708014 0.82 ALDH1A1 (0.48) ALDH1A1TSHRERN1TYRTRIM24
SCHEMBL16232872 0.82 NPSR1 (0.42) ALDH1A1ERN1TYRTRIM24TRIM33
SCHEMBL29952866 0.78 TRIM24 (0.47) ALDH1A1ERN1TYRTRIM24TRIM33
SCHEMBL7913737 0.78 TRIM24 (0.47) ALDH1A1ERN1TYRTRIM24TRIM33
SCHEMBL15146899 0.77 ESR2 (0.45) TSHRACHEMAPTHSD17B10CYP3A4
Phenol SCHEMBL3674570 0.77 ALDH1A1 (0.48) ALDH1A1TSHRERN1ACHETRIM24
SCHEMBL268706 0.76 ALDH1A1 (0.52) ALDH1A1TSHRERN1KDM4EGAA
SCHEMBL36835 0.76 ERN1 (0.61) ALDH1A1ERN1TRIM24TRIM33KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117402167-A Tanshinone benzimidazole type fluorescent probe, preparation method and application thereof in detecting BF 3 Application in (a) 南京林业大学 2024-01-16 CN claimed
JP-4587669-B2 2010-11-24 JP claimed
JP-2005509662-A 2005-04-14 JP claimed
CN-1589136-A Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups CUTANIX CORP (US) 2005-03-02 CN claimed
EP-1443915-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES Cutanix Corporation (US) 2004-08-11 EP claimed
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments CUTANIX CORPORATION 2003-08-21 US claimed
WO-2003043621-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES CUTANIX CORPORATION (US) 2003-05-30 WO claimed
EP-4716685-A1 IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER F. Hoffmann-La Roche AG (CH) 2026-04-01 EP disclosed
US-20260070906-A1 IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER HOFFMANN-LA ROCHE INC. (US) 2026-03-12 US disclosed
US-20250353874-A1 GLUCOCORTICOID RECEPTOR AGONISTS LILLY CO ELI (US) 2025-11-20 US disclosed
US-12404298-B2 Glucocorticoid receptor agonists ELI LILLY AND COMPANY (US) 2025-09-02 US disclosed
WO-2024240726-A1 IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER F. HOFFMANN-LA ROCHE AG (CH) 2024-11-28 WO disclosed
CN-117843515-A Aromatic amino acid derivative as LAT1 inhibitor and preparation method and application thereof 中国药科大学 2024-04-09 CN disclosed
US-4526912-A Phenoxy resin and mixture of phenolic resins, melamine resins, polyisocyanates THE P. D. GEORGE CO. (US) 1985-07-02 US disclosed
EP-0081125-B1 CATIONIC DYES, THEIR PREPARATION PROCESS AND THEIR USE IN DYEING AND MASS DYEING BAYER AG (DE) 1985-05-08 EP disclosed
EP-0000947-B2 3,4,5-TRIHYDROXYPIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS AND FODDER CONTAINING THEM BAYER AG (DE) 1984-10-10 EP disclosed
EP-0008058-B1 N-AMINO-3,4,5-TRIHYDROXYPIPERIDINES, METHODS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, METHOD FOR THE PRODUCTION OF THE MEDICAMENTS AND ANIMAL FEEDSTUFF CONTAINING SAID COMPOUNDS BAYER AG (DE) 1982-08-18 EP disclosed
EP-0000947-B1 3,4,5-TRIHYDROXYPIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS AND FODDER CONTAINING THEM BAYER AG (DE) 1981-01-14 EP disclosed
EP-0008058-A1 N-Amino-3,4,5-trihydroxypiperidines, methods for their preparation, medicaments containing them, method for the production of the medicaments and animal feedstuff containing said compounds BAYER AG (DE) 1980-02-20 EP disclosed
EP-0000947-A1 3,4,5-Trihydroxypiperidine derivatives, process for their preparation and medicaments and fodder containing them BAYER AG (DE) 1979-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments TYR, HRH1, HRH2 ALDH1A1 7/4885TSHR 4382/4885ERN1 4830/4885
US-12404298-B2 Glucocorticoid receptor agonists NR3C1, NR3C2, MC2R ALDH1A1 3227/4885TSHR 193/4885ERN1 1650/4885
US-20250353874-A1 GLUCOCORTICOID RECEPTOR AGONISTS NR3C1, NR3C2, MC2R ALDH1A1 3227/4885TSHR 193/4885ERN1 1650/4885
US-20260070906-A1 IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER TLR1, TLR6, TLR8 ALDH1A1 1320/4885TSHR 1070/4885ERN1 2137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.