Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 4/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431568 | 0.74 | RXRA (0.44) | PIN1GRIN1GRIN2BPARP1ALDH1A1 | |
| SCHEMBL3431645 | 0.73 | RXRA (0.43) | PIN1GRIN1GRIN2BPARP1GRK6 | |
| SCHEMBL3346056 | 0.72 | S1PR1 (0.41) | EGLN1 | |
| SCHEMBL3346086 | 0.70 | PTGER4 (0.44) | GRIN1GRIN2BPARP1 | |
| SCHEMBL3353013 | 0.70 | DHODH (0.45) | CTSAGRIN1GRIN2BXDHMGLL | |
| SCHEMBL3347691 | 0.69 | FFAR4 (0.40) | GRIN1GRIN2BPDE2A | |
| SCHEMBL3430749 | 0.67 | GAA (0.43) | GRIN1GRIN2B | |
| SCHEMBL3431483 | 0.67 | FFAR1 (0.43) | CTSAXDHMMEMGLL | |
| SCHEMBL3475918 | 0.67 | GRIN2B (0.41) | CTSAPIN1GRIN1GRIN2BALDH1A1 | |
| SCHEMBL3435475 | 0.67 | GRIN2B (0.41) | CTSAPIN1GRIN1GRIN2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | claimed |