Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430772 | 0.91 | KDM4E (0.38) | KDM4EHSD17B10TP53MAPTALOX15 | |
| SCHEMBL3346362 | 0.88 | DHODH (0.39) | DHODHPIM1PIM2XDHKDM4E | |
| SCHEMBL3352922 | 0.76 | GSK3B (0.38) | DHODHPIM1PIM2 | |
| SCHEMBL3430044 | 0.74 | FFAR1 (0.48) | DHODHPIM1PIM2XDH | |
| SCHEMBL3428421 | 0.73 | PPARD (0.39) | PIM1PIM2 | |
| SCHEMBL3431483 | 0.72 | FFAR1 (0.43) | DHODHPIM1PIM2XDHSUCNR1 | |
| SCHEMBL3353013 | 0.71 | DHODH (0.45) | DHODHPIM1PIM2XDHGRIN1 | |
| SCHEMBL3434810 | 0.70 | SCD (0.46) | TRPV3TRPA1GRIN1GRIN2BSUCNR1 | |
| SCHEMBL3349649 | 0.70 | FFAR1 (0.45) | DHODHPIM1PIM2XDHHPGD | |
| SCHEMBL3432976 | 0.70 | GSK3B (0.39) | KDM4EHSD17B10MAPTHPGDTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | disclosed |