Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430772 | 0.78 | KDM4E (0.38) | GSK3BKDM4EHSD17B10TRPV1TSHR | |
| SCHEMBL3346362 | 0.75 | DHODH (0.39) | KDM4EHSD17B10TRPV1TSHRALDH1A1 | |
| SCHEMBL3344258 | 0.71 | KDM4E (0.43) | GSK3BKDM4EHSD17B10TRPV1TSHR | |
| SCHEMBL3475197 | 0.70 | SCD (0.47) | — | |
| SCHEMBL3430136 | 0.70 | DHODH (0.39) | KDM4EHSD17B10TRPV1HPGDMAPT | |
| SCHEMBL3352922 | 0.70 | GSK3B (0.38) | GSK3B | |
| SCHEMBL3352967 | 0.69 | NR1D1 (0.40) | GSK3BKDM4EHSD17B10TRPV1TSHR | |
| SCHEMBL3428421 | 0.69 | PPARD (0.39) | GSK3B | |
| SCHEMBL3430623 | 0.67 | FFAR1 (0.43) | KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL4493825 | 0.66 | GSK3B (0.78) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | claimed |