SCHEMBL343426

SCHEMBL343426

BC(C)(C)C(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
RIPK1 Q13546 2/20 0.40
DPP4 P27487 2/20 0.38
HRH1 P35367 2/20 0.38
AOC3 Q16853 1/20 0.38
F2 P00734 1/20 0.38
TSHR P16473 1/20 0.38
CACNA1F O60840 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
ADRA2B P18089 1/20 0.38
CHRM3 P20309 1/20 0.38
ADRA1A P35348 1/20 0.38
OPRK1 P41145 1/20 0.38
CACNA1D Q01668 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KCNH2 Q12809 1/20 0.38
CACNA1S Q13698 1/20 0.38
CACNA1C Q13936 1/20 0.38
SCN5A Q14524 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5029899 0.78 RIPK1 (0.43) LMNARIPK1DPP4HRH1AOC3
SCHEMBL25768136 0.77 RIPK1 (0.43) LMNARIPK1HRH1AOC3CACNA1F
SCHEMBL28817806 0.74 RIPK1 (0.40) LMNARIPK1DPP4HRH1AOC3
SCHEMBL352841 0.74 TAAR1 (0.46) LMNARIPK1DPP4AOC3F2
SCHEMBL1132470 0.74 LMNA (0.41) LMNARIPK1DPP4HRH1AOC3
SCHEMBL23880379 0.74 RIPK1 (0.40) LMNARIPK1DPP4HRH1AOC3
SCHEMBL327102 0.74 RIPK1 (0.40) LMNARIPK1DPP4HRH1AOC3
SCHEMBL10476770 0.74 RIPK1 (0.43) LMNARIPK1DPP4AOC3SLC6A3
SCHEMBL3018884 0.74 RIPK1 (0.40) RIPK1DPP4HRH1AOC3F2
SCHEMBL2212637 0.74 RIPK1 (0.40) LMNARIPK1DPP4HRH1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024126126-A1 NEW ETHER-AMINE COMPOSITIONS AND THE USE THEREOF AS CURING AGENTS FOR EPOXY RESINS BASF SE (DE) 2024-06-20 WO claimed
WO-2024126126-A1 NEW ETHER-AMINE COMPOSITIONS AND THE USE THEREOF AS CURING AGENTS FOR EPOXY RESINS BASF SE (DE) 2024-06-20 WO disclosed
CN-106999802-B Defoaming agent 圣诺普科有限公司 2020-03-27 CN disclosed
EP-2562193-B1 POLYOL FOR POLYURETHANE PREPARATION AND POLYURETHANE PREPARATION METHOD USING SAME SANYO CHEMICAL IND LTD (JP) 2018-10-17 EP disclosed
EP-2290002-B1 POLYMER POLYOL AND METHOD FOR PRODUCING POLYURETHANE SANYO CHEMICAL IND LTD (JP) 2018-08-08 EP disclosed
US-20170312657-A1 DEFOAMING AGENT SAN NOPCO LTD. (JP) 2017-11-02 US disclosed
EP-2415798-B1 POLYOXYALKYLENE POLYOL OR MONOOL AND POLYURETHANE RESIN SANYO CHEMICAL IND LTD (JP) 2017-09-06 EP disclosed
US-9388271-B2 Polyoxyalkylene polyol or monool and polyurethane resin SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2016-07-12 US disclosed
US-9340640-B2 Polyol for polyurethane preparation and polyurethane preparation method using same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2016-05-17 US disclosed
EP-2562193-A1 POLYOL FOR POLYURETHANE PREPARATION AND POLYURETHANE PREPARATION METHOD USING SAME Sanyo Chemical Industries, Ltd. (JP) 2013-02-27 EP disclosed
US-20130030140-A1 POLYOL FOR POLYURETHANE PREPARATION AND POLYURETHANE PREPARATION METHOD USING SAME SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2013-01-31 US disclosed
EP-2415798-A1 POLYOXYALKYLENE POLYOL OR MONOOL AND POLYURETHANE RESIN Sanyo Chemical Industries, Ltd. (JP) 2012-02-08 EP disclosed
US-20120016049-A1 POLYOXYALKYLENE POLYOL OR MONOOL AND POLYURETHANE RESIN SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2012-01-19 US disclosed
US-20110086996-A1 POLYMER POLYOL AND METHOD FOR PRODUCING POLYURETHANE SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed
EP-2290002-A1 POLYMER POLYOL AND METHOD FOR PRODUCING POLYURETHANE Sanyo Chemical Industries, Ltd. (JP) 2011-03-02 EP disclosed
US-6831112-B2 A polyether polyol obtained by random and/or block addition of an alkylene oxide(including 1,2-alkylene oxide having not less than three carbon atoms as a principal constituents and also include ethyene oxide) to an active hydrogen compound SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2004-12-14 US disclosed
EP-1125961-B1 NOVEL POLYOXYALKYLENEPOLYOLS AND PROCESS FOR PRODUCING RING-OPENED POLYMER SANYO CHEMICAL IND LTD (JP) 2004-11-03 EP disclosed
US-20030100623-A1 Polyether, active-hydrogen ingredient , resin-forming composition, and process for producing foam SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2003-05-29 US disclosed
US-6531566-B1 Decyclization of ethers to form glycols used as monomers for thermosetting resins having higher molecular weights, tensile strength, flexibility or elasticity; raw matetrials for oils, detergents, antifoaming agents and/or surfactants SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2003-03-11 US disclosed
EP-1125961-A1 NOVEL POLYOXYALKYLENEPOLYOLS AND PROCESS FOR PRODUCING RING-OPENED POLYMER SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2001-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120016049-A1 POLYOXYALKYLENE POLYOL OR MONOOL AND POLYURETHANE RESIN FPR1, FPR2, XRCC5 LMNA 2035/4885RIPK1 3639/4885DPP4 4871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.