Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248146 | 0.93 | OPRM1 (0.48) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL11244168 | 0.91 | ADRB1 (0.46) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL1422064 | 0.85 | ADRB1 (0.49) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL11248120 | 0.82 | IDO1 (0.45) | CYP2C9ESR1ESR2OPRM1OPRK1 | |
| SCHEMBL1422359 | 0.81 | ADRB1 (0.49) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL21505015 | 0.81 | ADRB1 (0.49) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL1421994 | 0.81 | ADRB1 (0.46) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL8490584 | 0.81 | SIGMAR1 (0.59) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL1422088 | 0.80 | ADRB1 (0.45) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL8389404 | 0.80 | ESR1 (0.65) | LMNAKMT2ASIGMAR1BLMTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010147234-A1 | DIARYLAMIDE-SPIRODIAMINE DERIVATIVE | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-12-23 | — | — | WO | claimed |
| WO-2010029566-A2 | PROCESS FOR PREPARATION OF PHENOXYPROPANOL AMINES | INDOCO REMEDIES LIMITED (IN) | 2010-03-18 | — | — | WO | claimed |
| CN-1300079-C | New technology of synthesizing 4-[2-(cyclo propyl methoxy] ethyl] phenol | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2007-02-14 | — | — | CN | claimed |
| US-7019172-B2 | Process for preparation of S-(-)-betaxolol and salts thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-03-28 | — | — | US | claimed |
| US-20060004109-A1 | Cyclopropanating 1-(2-allyloxyethyl)-4-benzyloxybenzene by the Simmon-Smith reaction with Furukawa modification to obtain the enantiomer 1-benzyloxy-4-(2-cyclopropyl methoxyethyl)benzene of high purity; avoiding the use of highly lacrymatric and unstable cyclopropylmethyl halide | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-01-05 | — | — | US | claimed |
| CN-1651379-A | New technology of synthesizing 4-[2-(cyclo propyl methoxy] ethyl] phenol | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2005-08-10 | — | — | CN | claimed |
| EP-0931055-B1 | SELECTIVE ALKYLATION OF AN ALCOHOL SUBSTITUTED PHENOL COMPOUND | ABBOTT LAB (US) | 2001-11-07 | — | — | EP | claimed |
| EP-0931055-A1 | SELECTIVE ALKYLATION OF AN ALCOHOL SUBSTITUTED PHENOL COMPOUND | Abbott Laboratories (US) | 1999-07-28 | — | — | EP | claimed |
| WO-1998012172-A1 | SELECTIVE ALKYLATION OF AN ALCOHOL SUBSTITUTED PHENOL COMPOUND | ABBOTT LABORATORIES (US) | 1998-03-26 | — | — | WO | claimed |
| WO-2024042818-A1 | LAMINATE AND ORGANIC EL DISPLAY DEVICE | 住友化学株式会社 | 2024-02-29 | — | — | WO | disclosed |
| WO-2024038667-A1 | OPTICAL LAMINATED BODY AND METHOD FOR MANUFACTURING SAME | 住友化学株式会社 | 2024-02-22 | — | — | WO | disclosed |
| WO-2024024119-A1 | OPTICAL LAMINATE | 住友化学株式会社 | 2024-02-01 | — | — | WO | disclosed |
| WO-2023153098-A1 | OPTICAL LAMINATE | 住友化学株式会社 | 2023-08-17 | — | — | WO | disclosed |
| WO-2023100716-A1 | CIRCULARLY POLARIZING PLATE WITH ADHESIVE LAYER | 住友化学株式会社 | 2023-06-08 | — | — | WO | disclosed |
| US-4652563-A | PYRIDAZINONES SUBSTITUTED WITH CYCLOPROPYLMETHOXYETHYL GROUP | SMITH KLINE & FRENCH LABORATORIES LTD. (GB) | 1987-03-24 | — | — | US | disclosed |
| WO-1986006368-A1 | STEREOSELECTIVE PROCESS AND CHIRAL INTERMEDIATES FOR ARYLOXYDROPANOLAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-11-06 | — | — | WO | disclosed |
| EP-0168921-A2 | Chemical compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-01-22 | — | — | EP | disclosed |
| EP-0045964-A1 | Derivatives of 3-amino-1,2-propane diol | CIBA-GEIGY AG (CH) | 1982-02-17 | — | — | EP | disclosed |
| US-4311708-A | ADRENERGIC BLOCKING AGENTS | SYNTHELABO (FR) | 1982-01-19 | — | — | US | disclosed |
| US-4252984-A | 1-/P-/2-/CYCLOPROPYLMETHOXY/ETHYL/PHENOXY/-3-ISOPROPYLAMINO-2 -PROPANOL | SYNTHELABO (FR) | 1981-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004109-A1 | Cyclopropanating 1-(2-allyloxyethyl)-4-benzyloxybenzene by the Simmon-Smith reaction with Furukawa modification to obtain the enantiomer 1-benzyloxy-4-(2-cyclopropyl methoxyethyl)benzene of high purity; avoiding the use of highly lacrymatric and unstable cyclopropylmethyl halide | SMAD2, SPHK1, TGFBR1 | ADRB1 7/4885LMNA 2697/4885CYP2D6 1755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.