Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3433136 | 0.86 | GPR84 (0.49) | LMNAALDH1A1CYP1A2GPR84CA2 | |
| SCHEMBL11979054 | 0.84 | LMNA (0.53) | LMNAALDH1A1CYP1A2GPR84CA2 | |
| SCHEMBL3360046 | 0.78 | GRN (0.51) | LMNAALDH1A1CYP1A2GPR84CA2 | |
| SCHEMBL21185729 | 0.75 | ALDH1A1 (0.49) | LMNAALDH1A1CYP1A2GPR84CA2 | |
| SCHEMBL16543122 | 0.73 | CYP1A2 (0.61) | LMNAALDH1A1CYP1A2GPR84CA1 | |
| SCHEMBL6446972 | 0.72 | HSPA5 (0.60) | LMNAALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL28577021 | 0.72 | KDM4E (0.47) | LMNAALDH1A1CYP1A2GPR84CA2 | |
| SCHEMBL21185586 | 0.72 | KDM4E (0.47) | LMNAALDH1A1CYP1A2GPR84CA2 | |
| SCHEMBL6446970 | 0.72 | HSPA5 (0.60) | LMNAALDH1A1GAAHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28578292 | 0.71 | KDM4E (0.46) | LMNAALDH1A1CYP1A2GPR84CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236952-B2 | Preparations containing amino acids and orotic acid | Northern Innovations Holding Corp. (CA) | 2012-08-07 | — | — | US | disclosed |
| US-8236952-B2 | Preparations containing amino acids and orotic acid | Northern Innovations Holding Corp. (CA) | 2012-08-07 | — | — | US | disclosed |
| US-8236952-B2 | Preparations containing amino acids and orotic acid | Northern Innovations Holding Corp. (CA) | 2012-08-07 | — | — | US | disclosed |
| EP-2231622-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | Northern Innovations and Formulations Corp. (CA) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009076743-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | IOVATE T. & P. INC. (CA) | 2009-06-25 | — | — | WO | disclosed |
| WO-2009076743-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | IOVATE T. & P. INC. (CA) | 2009-06-25 | — | — | WO | disclosed |
| US-20090156812-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | US | disclosed |
| US-20090156812-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | US | disclosed |
| US-20090156812-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156812-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | DDC, ODC1, OTC | LMNA 4516/4885ALDH1A1 2765/4885CYP1A2 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.