SCHEMBL3433136

SCHEMBL3433136

CCC(C)C(NC(=O)c1cc(=O)[nH]c(=O)[nH]1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.49
CA2 P00918 3/20 0.45
CA1 P00915 2/20 0.45
ALDH1A1 P00352 2/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.44
AKR1B1 P15121 1/20 0.44
FPR2 P25090 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.41
TYR P14679 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PYGL P06737 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3434869 0.86 LMNA (0.50) GPR84CA2CA1ALDH1A1LMNA
SCHEMBL11979054 0.80 LMNA (0.53) GPR84CA2CA1ALDH1A1LMNA
SCHEMBL3360046 0.77 GRN (0.51) GPR84CA2CA1ALDH1A1LMNA
SCHEMBL21185729 0.73 ALDH1A1 (0.49) GPR84CA2CA1ALDH1A1LMNA
SCHEMBL15332731 0.72 CA2 (0.47) CA2CA1ALDH1A1FPR2MEN1
SCHEMBL29953517 0.72 CA2 (0.47) CA2CA1ALDH1A1FPR2MEN1
SCHEMBL21991765 0.71 GPR84 (0.69) GPR84CA1ALDH1A1LMNACYP1A2
SCHEMBL21185586 0.71 KDM4E (0.47) GPR84CA2CA1ALDH1A1LMNA
SCHEMBL3433459 0.70 GPR84 (0.41) GPR84CA2CA1ALDH1A1LMNA
SCHEMBL16543122 0.69 CYP1A2 (0.61) GPR84CA1ALDH1A1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236952-B2 Preparations containing amino acids and orotic acid Northern Innovations Holding Corp. (CA) 2012-08-07 US disclosed
US-8236952-B2 Preparations containing amino acids and orotic acid Northern Innovations Holding Corp. (CA) 2012-08-07 US disclosed
US-8236952-B2 Preparations containing amino acids and orotic acid Northern Innovations Holding Corp. (CA) 2012-08-07 US disclosed
EP-2231622-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID Northern Innovations and Formulations Corp. (CA) 2010-09-29 EP disclosed
WO-2009076743-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID IOVATE T. & P. INC. (CA) 2009-06-25 WO disclosed
WO-2009076743-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID IOVATE T. & P. INC. (CA) 2009-06-25 WO disclosed
US-20090156812-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID IOVATE T. & P. INC. (CA) 2009-06-18 US disclosed
US-20090156812-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID IOVATE T. & P. INC. (CA) 2009-06-18 US disclosed
US-20090156812-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID IOVATE T. & P. INC. (CA) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156812-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID DDC, ODC1, OTC GPR84 3114/4885CA2 566/4885CA1 95/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.