SCHEMBL343569

SCHEMBL343569

CCCc1ccccc1OC(=O)CN

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.48
THRB P10828 1/20 0.48
PPARD Q03181 1/20 0.47
TAAR1 Q96RJ0 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
RECQL P46063 1/20 0.42
KMT2A Q03164 1/20 0.42
LTB4R Q15722 1/20 0.41
LTB4R2 Q9NPC1 1/20 0.41
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6666131 0.98 THRA (0.47) THRATHRBPPARDTAAR1KDM4E
SCHEMBL7562292 0.90 THRA (0.56) THRATHRBPPARDTAAR1KDM4E
SCHEMBL15212670 0.88 L3MBTL1 (0.44) THRATHRBTAAR1KDM4EMEN1
SCHEMBL10694271 0.86 KDM4E (0.51) THRATHRBPPARDKDM4EMEN1
SCHEMBL1839407 0.83 THRA (0.50) THRATHRBPPARDTAAR1MEN1
SCHEMBL30409585 0.83 THRA (0.50) THRATHRBPPARDTAAR1MEN1
SCHEMBL7065312 0.82 THRA (0.53) THRATHRBPPARDLTB4RLTB4R2
SCHEMBL28064699 0.82 L3MBTL1 (0.40) THRATHRBTAAR1KDM4EMEN1
SCHEMBL29581614 0.82 THRA (0.53) THRATHRBPPARDLTB4RLTB4R2
SCHEMBL729676 0.82 THRA (0.53) THRATHRBPPARDLTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325463-A1 COMPOSITIONS (III) SYMRISE AG (DE) 2025-10-23 US claimed
EP-4602141-A1 A FRAGRANCE MIXTURE (VI) Symrise AG (DE) 2025-08-20 EP claimed
EP-4532646-A1 A FRAGRANCE MIXTURE (V) Symrise AG (DE) 2025-04-09 EP claimed
US-20250099349-A1 A FRAGRANCE MIXTURE SYMRISE AG (DE) 2025-03-27 US claimed
EP-4519403-A1 A FRAGRANCE MIXTURE (V) Symrise AG (DE) 2025-03-12 EP claimed
EP-4473079-A1 A FRAGRANCE MIXTURE Symrise AG (DE) 2024-12-11 EP claimed
EP-4472606-A1 COMPOSITIONS (III) Symrise AG (DE) 2024-12-11 EP claimed
US-20240358611-A1 COMPOSITIONS SYMRISE AG (DE) 2024-10-31 US claimed
EP-4429465-A1 COMPOSITIONS COMPRISING TRPM8 AGONISTIC COOLING AGENTS Symrise AG (DE) 2024-09-18 EP claimed
EP-4387587-A1 COMPOSITIONS Symrise AG (DE) 2024-06-26 EP claimed
WO-2023147874-A1 A FRAGRANCE MIXTURE SYMRISE AG (DE) 2023-08-10 WO claimed
WO-2023147852-A1 COMPOSITIONS (III) SYMRISE AG (DE) 2023-08-10 WO claimed
WO-2023083445-A1 COMPOSITIONS COMPRISING TRPM8 AGONISTIC COOLING AGENTS SYMRISE AG (DE) 2023-05-19 WO claimed
WO-2023021012-A1 COMPOSITIONS SYMRISE AG (DE) 2023-02-23 WO claimed
US-11344857-B2 Microcapsules SYMRISE AG (DE) 2022-05-31 US claimed
US-11116712-B2 Fragrance composition SYMRISE AG (DE) 2021-09-14 US claimed
EP-1660621-B1 AGENTS THAT ARE ABSORBED BY THE SURFACE OF SUBSTRATES HENKEL AG & CO KGAA (DE) 2012-02-01 EP claimed
US-7446086-B2 Agents that are absorbed on the surfaces of substrates HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-11-04 US claimed
US-20060229230-A1 Agents that are absorbed on the surfaces of substrates HENKEL AG & CO. KGAA (DE) 2006-10-12 US claimed
EP-1062164-B1 CONTAINER FOR AQUEOUS HYPOCHLORITE-BASED BLEACHING AGENTS HENKEL KGAA (DE) 2003-07-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358611-A1 COMPOSITIONS AZI2, NISCH, CIP2A THRA 2803/4885THRB 3748/4885PPARD 2298/4885
US-20250099349-A1 A FRAGRANCE MIXTURE PTMS, EP300, TRPA1 THRA 2211/4885THRB 1844/4885PPARD 187/4885
US-11116712-B2 Fragrance composition NISCH, CUTA, CYP1B1 THRA 3798/4885THRB 4252/4885PPARD 780/4885
US-20250325463-A1 COMPOSITIONS (III) NISCH, TAS1R3, TAS2R3 THRA 1982/4885THRB 1553/4885PPARD 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.