SCHEMBL3437330

SCHEMBL3437330

CCCC1CCC(C2CCC(CCc3ccc(OCC)c(F)c3F)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.33
TLR4 O00206 1/20 0.32
CTSL P07711 1/20 0.32
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30
CYP2C9 P11712 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22277545 1.00 KDM1A (0.33) KDM1ATLR4CTSLCTSSCTSK
SCHEMBL9405829 0.96 KDM1A (0.35) KDM1ACTSLCTSSCTSKFFAR4
SCHEMBL3437363 0.96 KDM1A (0.35) KDM1ACTSLCTSSCTSKFFAR4
SCHEMBL12032161 0.95 TLR4 (0.34) KDM1ATLR4
SCHEMBL9630399 0.92 RIPK1 (0.38) TLR4CTSLCTSSCTSKHTR2A
SCHEMBL3437343 0.92 CYP1A2 (0.33) KDM1ACTSLCTSSCTSKHTR2A
SCHEMBL9630395 0.92 RIPK1 (0.38) TLR4CTSLCTSSCTSKHTR2A
SCHEMBL16501541 0.92 SLC6A2 (0.32) KDM1ATLR4CTSLCTSSCTSK
SCHEMBL16769034 0.92 CACNA2D1 (0.34) KDM1AHTR2AHTR2C
SCHEMBL16769040 0.92 KDM1A (0.33) KDM1AHTR2AHTR2CFFAR4KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10934488-B2 Polymerizable compound-containing liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2021-03-02 US disclosed
US-20200183203-A1 REVERSE MODE LIQUID CRYSTAL DEVICE JNC CORPORATION (JP) 2020-06-11 US disclosed
US-20200071617-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-03-05 US disclosed
US-10519377-B1 Liquid crystal composition of negative monomer containing cyclopentyl cyclohexenyl and liquid crystal display element or liquid crystal display thereof Shijiazhuang Chengzhi Yonghua Display Material Co., Ltd (CN) 2019-12-31 US disclosed
EP-3553595-A1 REVERSE MODE LIQUID CRYSTAL DEVICE JNC Corporation (JP) 2019-10-16 EP disclosed
US-20190233730-A1 POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2019-08-01 US disclosed
US-10308873-B2 Polymerizable compound-containing liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2019-06-04 US disclosed
US-10294425-B2 Liquid crystal composition and liquid crystal display device JCN CORPORATION (JP) 2019-05-21 US disclosed
US-10287502-B2 Liquid crystal composition containing polymerizable compound and liquid crystal display element using the same DIC Corporation (Tokyo) (JP) 2019-05-14 US disclosed
US-10035955-B2 Liquid-crystal display element DIC CORPORATION (JP) 2018-07-31 US disclosed
US-20110141418-A1 LIQUID CRYSTAL COMPOUNDS QINETIQ LIMITED (GB) 2011-06-16 US disclosed
US-7718232-B2 Nematic liquid crystal composition and liquid crystal display element that used the composition DAINIPPON INK & CHEMICAL, INC. (JP) 2010-05-18 US disclosed
US-7670504-B2 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK & CHEMICALS, INC. (JP) 2010-03-02 US disclosed
US-7670504-B2 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK & CHEMICALS, INC. (JP) 2010-03-02 US disclosed
US-7651630-B2 Difluorobenzene derivative and nematic liquid crystal composition using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2010-01-26 US disclosed
US-20090050843-A1 DIFLUOROBENZENE DERIVATIVE AND NEMATIC LIQUID CRYSTAL COMPOSITION USING THE SAME DAINIPPON INK AND CHEMICALS, INC. (JP) 2009-02-26 US disclosed
US-20080149889-A1 Nematic Liquid Crystal Composition and Liquid Crystal Display Element That Used the Composition DAINIPPON INK AND CHEMICALS, INC. (JP) 2008-06-26 US disclosed
US-20080111107-A1 Nematic Liquid Crystal Composition And Liquid Crystal Display Device Using The Same DAINIPPON INK AND CHEMICALS, INC. (JP) 2008-05-15 US disclosed
EP-1860089-A1 DIFLUOROBENZENE DERIVATIVE AND NEMATIC LIQUID CRYSTAL COMPOSITION MAKING USE OF THE SAME Dainippon Ink and Chemicals, Incorporated (JP) 2007-11-28 EP disclosed
US-7226644-B2 Chroman derivative and liquid-crystal composition containing the compound DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090050843-A1 DIFLUOROBENZENE DERIVATIVE AND NEMATIC LIQUID CRYSTAL COMPOSITION USING THE SAME HCN2, TRPV2, TRPV5 KDM1A 2091/4885TLR4 4691/4885CTSL 4770/4885
US-20110141418-A1 LIQUID CRYSTAL COMPOUNDS HTR3D, HTR3C, SFXN3 KDM1A 3188/4885TLR4 1581/4885CTSL 618/4885
US-20080111107-A1 Nematic Liquid Crystal Composition And Liquid Crystal Display Device Using The Same PIEZO1, KIF20B, VCL KDM1A 1567/4885TLR4 4064/4885CTSL 3424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.