Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 7/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 2/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3441752 | 0.86 | SMN1; SMN2 (0.39) | ELOVL1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL4667721 | 0.85 | ELOVL1 (0.49) | ELOVL1ALDH1A1L3MBTL1KCNQ2KCNQ3 | |
| SCHEMBL3441880 | 0.83 | TSHR (0.45) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL3441699 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KCNQ2KCNQ3POLBMEN1 | |
| SCHEMBL3441644 | 0.82 | AKT1 (0.35) | ALDH1A1CYP1A2CYP2D6POLBCRHBP | |
| SCHEMBL3441392 | 0.81 | CACNA1G (0.42) | ELOVL1ALDH1A1KMT2ALMNAHTT | |
| SCHEMBL3441522 | 0.81 | HSD17B10 (0.38) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL3441887 | 0.80 | ALDH1A1 (0.35) | ALDH1A1POLBHTTSMN1; SMN2MAPT | |
| SCHEMBL3441894 | 0.80 | TSHR (0.44) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL3441444 | 0.80 | ALDH1A1 (0.44) | ALDH1A1POLBKMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812026-B2 | Imidazole derivatives having a positive allosteric GABAB receptor modulator effect and methods of use | ASTRAZENECA AB (SE) | 2010-10-12 | — | — | US | claimed |
| US-20090149474-A1 | GABA-B RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2009-06-11 | — | — | US | claimed |
| US-7812026-B2 | Imidazole derivatives having a positive allosteric GABAB receptor modulator effect and methods of use | ASTRAZENECA AB (SE) | 2010-10-12 | — | — | US | disclosed |
| US-7812026-B2 | Imidazole derivatives having a positive allosteric GABAB receptor modulator effect and methods of use | ASTRAZENECA AB (SE) | 2010-10-12 | — | — | US | disclosed |
| US-7812026-B2 | Imidazole derivatives having a positive allosteric GABAB receptor modulator effect and methods of use | ASTRAZENECA AB (SE) | 2010-10-12 | — | — | US | disclosed |
| US-20090149474-A1 | GABA-B RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2009-06-11 | — | — | US | disclosed |
| US-20090149474-A1 | GABA-B RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2009-06-11 | — | — | US | disclosed |
| US-20090149474-A1 | GABA-B RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149474-A1 | GABA-B RECEPTOR MODULATORS | GABRB1, GABBR2, GABRB2 | ELOVL1 3776/4885ALDH1A1 1302/4885L3MBTL1 3291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.