Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3448424 | 0.93 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1F10ACHEALDH1A1 | |
| SCHEMBL3450964 | 0.93 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1F10ACHEALDH1A1 | |
| SCHEMBL24802129 | 0.74 | ALDH1A1 (0.49) | L3MBTL3L3MBTL1F10ACHEALDH1A1 | |
| SCHEMBL24204406 | 0.72 | ALDH1A1 (0.45) | L3MBTL3L3MBTL1F10ACHEALDH1A1 | |
| SCHEMBL3450464 | 0.71 | ALDH1A1 (0.44) | L3MBTL3L3MBTL1F10ACHEALDH1A1 | |
| SCHEMBL4678853 | 0.71 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1F10ACHEALDH1A1 | |
| SCHEMBL3450967 | 0.70 | ALDH1A1 (0.43) | L3MBTL3L3MBTL1F10ACHEALDH1A1 | |
| SCHEMBL3448427 | 0.70 | ALDH1A1 (0.43) | L3MBTL3L3MBTL1F10ACHEALDH1A1 | |
| SCHEMBL3766167 | 0.70 | SIGMAR1 (0.50) | L3MBTL3L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL14834396 | 0.70 | LMNA (0.35) | L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820699-B2 | Cyclic amines | HOFFMANN-LA ROCHE INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-20060247238-A1 | Cyclic amines | F. HOFFMANN-LA ROCHE AG (CH) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247238-A1 | Cyclic amines | F12, F11, F2 | L3MBTL3 3721/4885L3MBTL1 4102/4885F10 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.