Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3450839 | 1.00 | MEN1 (0.41) | MEN1KMT2AABCB1NPC1RAB9A | |
| SCHEMBL24766843 | 0.82 | MEN1 (0.46) | MEN1KMT2AABCB1NPC1RAB9A | |
| SCHEMBL22100562 | 0.82 | MEN1 (0.46) | MEN1KMT2AABCB1NPC1RAB9A | |
| SCHEMBL9755795 | 0.80 | ABCB1 (0.48) | ABCB1NPC1RAB9AMAOBALDH1A1 | |
| SCHEMBL9755798 | 0.80 | ABCB1 (0.48) | ABCB1NPC1RAB9AMAOBALDH1A1 | |
| SCHEMBL15530737 | 0.79 | TSHR (0.43) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL10033420 | 0.79 | RORC (0.45) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL14085934 | 0.79 | MEN1 (0.43) | MEN1KMT2AABCB1NPC1RAB9A | |
| SCHEMBL13109044 | 0.77 | TRPA1 (0.46) | KMT2APOLBALDH1A1KDM4ELMNA | |
| SCHEMBL13657503 | 0.77 | MAOB (0.45) | MEN1KMT2AABCB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820858-B2 | Concise β2-amino acid synthesis via organocatalytic aminomethylation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820858-B2 | Concise β2-amino acid synthesis via organocatalytic aminomethylation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820858-B2 | Concise β2-amino acid synthesis via organocatalytic aminomethylation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-10-26 | — | — | US | disclosed |
| US-20080058548-A1 | CONCISE BETA2-AMINO ACID SYNTHESIS VIA ORGANOCATALYTIC AMINOMETHYLATION | WISCONSIN ALUMNI RESEARCH FOUNDATION (WARF) (US) | 2008-03-06 | — | — | US | disclosed |
| US-20080058548-A1 | CONCISE BETA2-AMINO ACID SYNTHESIS VIA ORGANOCATALYTIC AMINOMETHYLATION | WISCONSIN ALUMNI RESEARCH FOUNDATION (WARF) (US) | 2008-03-06 | — | — | US | disclosed |
| US-20080058548-A1 | CONCISE BETA2-AMINO ACID SYNTHESIS VIA ORGANOCATALYTIC AMINOMETHYLATION | WISCONSIN ALUMNI RESEARCH FOUNDATION (WARF) (US) | 2008-03-06 | — | — | US | disclosed |
| WO-2007112358-A1 | CONCISE BETA2-AMINO ACID SYNTHESIS VIA ORGANOCATALYTIC AMINOMETHYLATION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-10-04 | — | — | WO | disclosed |
| WO-2007112358-A1 | CONCISE BETA2-AMINO ACID SYNTHESIS VIA ORGANOCATALYTIC AMINOMETHYLATION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058548-A1 | CONCISE BETA2-AMINO ACID SYNTHESIS VIA ORGANOCATALYTIC AMINOMETHYLATION | BCAT2, AADAT, BCAT1 | MEN1 1584/4885KMT2A 341/4885ABCB1 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.