SCHEMBL3451231

SCHEMBL3451231

O=C1CC(c2ccc(O)c(O)c2)Oc2cc(OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc(O)c21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLCO2B1 O94956 3/20 1.00
▸ SYNJ2 O15056 1/20 1.00
▸ PTPN1 P18031 3/20 0.86
▸ KDM1A O60341 2/20 0.82
▸ PKM P14618 2/20 0.79
▸ DPP4 P27487 1/20 0.76
▸ GSK3B P49841 2/20 0.69
▸ CYP19A1 P11511 2/20 0.69
▸ UBE2N P61088 1/20 0.69
▸ POLB P06746 2/20 0.64
▸ TDP1 Q9NUW8 2/20 0.64
▸ MEN1 O00255 2/20 0.64
▸ KMT2A Q03164 2/20 0.64
▸ CALM1 P0DP23 1/20 0.64
▸ CACNA1B Q00975 1/20 0.64
▸ APBA1 Q02410 1/20 0.64
▸ CTDSP1 Q9GZU7 1/20 0.64
▸ TRPA1 O75762 1/20 0.63
▸ P4HB P07237 1/20 0.63
▸ TRPV1 Q8NER1 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20437868 1.00 SLCO2B1 (1.00) SLCO2B1SYNJ2PTPN1KDM1APKM
SCHEMBL292299 1.00 SLCO2B1 (1.00) SLCO2B1SYNJ2PTPN1KDM1APKM
SCHEMBL28281120 1.00 SLCO2B1 (1.00) SLCO2B1SYNJ2PTPN1KDM1APKM
SCHEMBL29559106 1.00 SLCO2B1 (1.00) SLCO2B1SYNJ2PTPN1KDM1APKM
SCHEMBL3934884 1.00 SLCO2B1 (1.00) SLCO2B1SYNJ2PTPN1KDM1APKM
Prunin SCHEMBL1122487 0.93 SLCO2B1 (1.00) SLCO2B1SYNJ2PTPN1KDM1APKM
Prunin SCHEMBL2532187 0.93 SLCO2B1 (1.00) SLCO2B1SYNJ2PTPN1KDM1APKM
Prunin SCHEMBL31233345 0.93 SLCO2B1 (1.00) SLCO2B1SYNJ2PTPN1KDM1APKM
Prunin SCHEMBL318230 0.93 SLCO2B1 (1.00) SLCO2B1SYNJ2PTPN1KDM1APKM
Prunin SCHEMBL31233342 0.93 SLCO2B1 (1.00) SLCO2B1SYNJ2PTPN1KDM1APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7829099-B2 Self-adhesive polymer matrix containing sea algae extract and glycerin BEIERSDORF AG (DE) 2010-11-09 — — US disclosed
US-7820177-B2 Self-adhesive polymer matrix containing a seaweed extract BEIERSDORF AG (DE) 2010-10-26 — — US disclosed
US-20050281869-A1 Self-adhesive polymer matrix containing a seaweed extract BEIERSDORF AG (DE) 2005-12-22 — — US disclosed
US-20050281881-A1 Self-adhesive polymer matrix containing sea algae extract and glycerin BEIERSDORF AG (DE) 2005-12-22 — — US disclosed
US-20050053634-A1 Detergent surfactants having a hydrophilic-lipophilic balance (HLB) of higher than 15, oil components, talc, polyacrylates and water; leaves a silky-smooth feel; prophylaxis of inflammatory skin conditions; do not contain an emulsifier in the conventional sense; shampoo, foam bath, cream BEIERSDORF AG (DE) 2005-03-10 — — US disclosed
US-20050002994-A1 Cosmetic or dermatological impregnated tissues BEIERSDORF AG (DE) 2005-01-06 — — US disclosed
US-20040265261-A1 Cleansing emulsion BEIERSDORF AG (DE) 2004-12-30 — — US disclosed
US-20040258647-A1 Active ingredient-containing cosmetic cleansing emulsions BEIERSDORF AG (DE) 2004-12-23 — — US disclosed
US-20040161454-A1 Active ingredient-containing matrix patches BEIERSDORF AG (DE) 2004-08-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050281881-A1 Self-adhesive polymer matrix containing sea algae extract and glycerin ALG1, ALG8, DSG1 SLCO2B1 4075/4885SYNJ2 863/4885PTPN1 4772/4885
US-20040161454-A1 Active ingredient-containing matrix patches CUTA, COL14A1, MMP1 SLCO2B1 1674/4885SYNJ2 2557/4885PTPN1 3363/4885
US-20050053634-A1 Detergent surfactants having a hydrophilic-lipophilic balance (HLB) of higher than 15, oil components, talc, polyacrylates and water; leaves a silky-smooth feel; prophylaxis of inflammatory skin conditions; do not contain an emulsifier in the conventional sense; shampoo, foam bath, cream CUTA, LRBA, LIPC SLCO2B1 3553/4885SYNJ2 544/4885PTPN1 1756/4885
US-20040258647-A1 Active ingredient-containing cosmetic cleansing emulsions CUTA, LIPA, ABHD16A SLCO2B1 3728/4885SYNJ2 1848/4885PTPN1 2199/4885
US-20040265261-A1 Cleansing emulsion SMURF1, SMURF2, DSG1 SLCO2B1 3233/4885SYNJ2 295/4885PTPN1 851/4885
US-20050281869-A1 Self-adhesive polymer matrix containing a seaweed extract EPCAM, CD44, ALG8 SLCO2B1 3975/4885SYNJ2 1534/4885PTPN1 4715/4885
US-20050002994-A1 Cosmetic or dermatological impregnated tissues CUTA, KAT8, PWWP2B SLCO2B1 1997/4885SYNJ2 546/4885PTPN1 1256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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