SCHEMBL345281

SCHEMBL345281

CCC(C(=O)O)=C(c1ccc(OC)cc1)c1ccc(OC)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.55
CA2 P00918 5/20 0.55
NR1I2 O75469 1/20 0.53
CES2 O00748 2/20 0.52
CES1 P23141 2/20 0.52
GSK3B P49841 1/20 0.49
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC10 Q969S8 1/20 0.49
HDAC11 Q96DB2 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
HDAC9 Q9UKV0 1/20 0.49
HDAC5 Q9UQL6 1/20 0.49
PARP1 P09874 1/20 0.48
PARP10 Q53GL7 1/20 0.48
PARP2 Q9UGN5 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9179233 0.84 PDE4B (0.58) CA1CA2CES2CES1GSK3B
SCHEMBL3250283 0.84 CA1 (0.53) CA1CA2NR1I2CES2CES1
SCHEMBL3250292 0.84 CA1 (0.53) CA1CA2NR1I2CES2CES1
SCHEMBL5052531 0.80 HDAC3 (0.49) CA1CA2NR1I2CES2CES1
SCHEMBL7922898 0.80 CES2 (0.57) CA1CA2CES2CES1PTGS2
SCHEMBL7922894 0.80 CES2 (0.57) CA1CA2CES2CES1PTGS2
SCHEMBL10981527 0.80 CYP19A1 (0.59) CA1CA2CES2CES1HDAC3
SCHEMBL10981521 0.80 CYP19A1 (0.59) CA1CA2CES2CES1HDAC3
SCHEMBL9177668 0.80 ALDH1A1 (0.52) PARP10PDE4BSMN1; SMN2KDM4EALDH1A1
SCHEMBL9177671 0.80 ALDH1A1 (0.52) PARP10PDE4BSMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2847784-B1 POLISHING PAD WITH LIGHT-STABLE LIGHT-TRANSMITTING REGION CABOT MICROELECTRONICS CORP (US) 2017-07-05 EP claimed
US-9156125-B2 Polishing pad with light-stable light-transmitting region CABOT MICROELECTRONICS CORPORATION (US) 2015-10-13 US claimed
US-20130273813-A1 POLISHING PAD WITH LIGHT-STABLE LIGHT-TRANSMITTING REGION CABOT MICROELECTRONICS CORPORATION (US) 2013-10-17 US claimed
EP-1100447-B1 SUNSCREEN COMPOSITIONS PROCTER & GAMBLE (US) 2004-05-12 EP claimed
EP-1100447-A1 SUNSCREEN COMPOSITIONS The Procter & Gamble Company (US) 2001-05-23 EP claimed
WO-2000006110-A1 SUNSCREEN COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-02-10 WO claimed
US-5989528-A Sunscreen compositions THE PROCTER & GAMBLE COMPANY (US) 1999-11-23 US claimed
US-10900168-B2 Fabric treatment for stain repellency van Buskirk, Gregory (US) 2021-01-26 US disclosed
US-10577743-B2 Laundry additive for providing antimicrobial effects to fabrics and interior surfaces of washing machine VAN BUSKIRK GREGORY (US) 2020-03-03 US disclosed
US-20180298552-A9 Laundry Additive for Providing Antimicrobial Effects to Fabrics and Washing Machine Surfaces VAN BUSKIRK GREGORY (US) 2018-10-18 US disclosed
EP-2847784-B1 POLISHING PAD WITH LIGHT-STABLE LIGHT-TRANSMITTING REGION CABOT MICROELECTRONICS CORP (US) 2017-07-05 EP disclosed
US-20160145795-A1 Fabric Treatments for Stain Release VAN BUSKIRK, GREGORY 2016-05-26 US disclosed
US-20150330020-A1 Laundry Additive for Providing Antimicrobial Effects to Fabrics and Washing Machine Surfaces VAN BUSKIRK GREGORY (US) 2015-11-19 US disclosed
US-20020028184-A1 Cosmetic compositions THE PROCTER & GAMBLE COMPANY 2002-03-07 US disclosed
WO-2002003951-A2 COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2002-01-17 WO disclosed
WO-2002003950-A2 COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2002-01-17 WO disclosed
WO-2001089466-A1 SKIN CARE MOISTURIZING AND SUNSCREEN COMPOSITIONS COMPRISING ORGANIC PARTICULATE MATERIAL THE PROCTER & GAMBLE COMPANY (US) 2001-11-29 WO disclosed
EP-1100447-A1 SUNSCREEN COMPOSITIONS The Procter & Gamble Company (US) 2001-05-23 EP disclosed
WO-2000006110-A1 SUNSCREEN COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-02-10 WO disclosed
US-5989528-A Sunscreen compositions THE PROCTER & GAMBLE COMPANY (US) 1999-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020028184-A1 Cosmetic compositions LAGE3, CUTA, SGMS2 CA1 4711/4885CA2 4011/4885NR1I2 2598/4885
US-10577743-B2 Laundry additive for providing antimicrobial effects to fabrics and interior surfaces of washing machine CUTA, MGLL, CD68 CA1 3368/4885CA2 3120/4885NR1I2 4201/4885
US-20180298552-A9 Laundry Additive for Providing Antimicrobial Effects to Fabrics and Washing Machine Surfaces CUTA, MGLL, POLL CA1 3647/4885CA2 3345/4885NR1I2 4244/4885
US-20150330020-A1 Laundry Additive for Providing Antimicrobial Effects to Fabrics and Washing Machine Surfaces CUTA, MGLL, POLL CA1 3647/4885CA2 3345/4885NR1I2 4244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.