Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MLNR | O43193 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CTSC | P53634 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454571 | 0.74 | CTSC (0.34) | CTSCMMP1MMP2MMP3MMP7 | |
| SCHEMBL3456238 | 0.69 | GPR119 (0.35) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL22324769 | 0.67 | SLC18A3 (0.48) | PSIP1GAA | |
| SCHEMBL4777240 | 0.65 | GBA1 (0.54) | PSIP1GAAMLNR | |
| Hydrochloric Acid SCHEMBL4773264 | 0.64 | GBA1 (0.53) | PSIP1GAAMLNR | |
| SCHEMBL3072064 | 0.63 | SYK (0.44) | MLNRCYP2D6JAK2 | |
| SCHEMBL3454499 | 0.62 | HTR6 (0.33) | PSIP1GAAMLNRCYP2D6JAK2 | |
| SCHEMBL27786329 | 0.61 | MMP1 (0.35) | MLNRCYP2D6CTSCJAK2MMP1 | |
| SCHEMBL3454488 | 0.60 | CNR2 (0.34) | PSIP1MLNRCYP2D6JAK2 | |
| Hydrochloric Acid SCHEMBL27808140 | 0.60 | MMP1 (0.35) | GAAMLNRCYP2D6CTSCJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2166850-A1 | NEW HETEOCYCLIC H3 ANTAGONISTS | High Point Pharmaceuticals, LLC (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008154126-A1 | NEW HETEOCYCLIC H3 ANTAGONISTS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2008-12-18 | — | — | WO | disclosed |