Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27520667 | 0.88 | CHRNB2 (0.39) | CHRNB2CHRNA4MEN1GAAKMT2A | |
| SCHEMBL345589 | 0.82 | HTR2A (0.42) | CHRNB2CHRNA4MEN1GAAKMT2A | |
| SCHEMBL2710155 | 0.81 | G6PD (0.36) | CHRNB2CHRNA4MEN1GAAKMT2A | |
| SCHEMBL4614491 | 0.81 | SCN9A (0.34) | CHRNB2CHRNA4MEN1GAAKMT2A | |
| SCHEMBL27199179 | 0.81 | SCN9A (0.34) | MEN1GAAKMT2ASCN9AADAMTS4 | |
| SCHEMBL15531515 | 0.80 | TRPA1 (0.41) | CHRNB2CHRNA4MEN1KMT2ASCN9A | |
| SCHEMBL27797604 | 0.80 | CHRNB2 (0.34) | CHRNB2CHRNA4SCN9AHTR2AHTR2C | |
| SCHEMBL5365399 | 0.76 | SMN1; SMN2 (0.38) | MEN1GAAKMT2AHTR2AHTR2C | |
| SCHEMBL15531513 | 0.73 | ALDH1A1 (0.45) | MEN1GAAKMT2ASCN9AHTR2A | |
| SCHEMBL6860646 | 0.72 | INPPL1 (0.44) | SCN9AHTR2AALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326397-B1 | OSTEOPOROSIS | HOFFMAN-LA ROCHE INC. | 2001-12-04 | — | — | US | disclosed |