Sulfuric Acid

Sulfuric Acid

SCHEMBL345780

NC(=O)COCC(N)=O.O=S(=O)(O)O

nearest known ligand 0.38

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 4/20 0.38
KDM4E B2RXH2 3/20 0.38
CA5A P35218 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
PMP22 Q01453 2/20 0.34
CYP2C19 P33261 2/20 0.33
TP53 P04637 2/20 0.33
GMNN O75496 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
THPO P40225 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL345383 0.87
SCHEMBL4652322 0.80
SCHEMBL2790638 0.77
SCHEMBL2010713 0.75 CES2 (0.37) BLMKDM4EPMP22CYP2C19TP53
SCHEMBL13258810 0.74
SCHEMBL30899223 0.74
SCHEMBL74242 0.74
SCHEMBL2353511 0.74 ALDH1A1 (0.38) BLMKDM4EPMP22CYP2C19TP53
SCHEMBL16016514 0.74
SCHEMBL24297077 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8765651-B2 Method of cleansing hair THE PROCTER & GAMBLE COMPANY (US) 2014-07-01 US claimed
EP-2593074-A2 COMPOSITIONS COMPRISING A NEAR TERMINAL-BRANCHED COMPOUND AND METHODS OF MAKING THE SAME The Procter and Gamble Company (US) 2013-05-22 EP claimed
EP-2593080-A2 METHOD OF CLEANSING HAIR The Procter and Gamble Company (US) 2013-05-22 EP claimed
US-20130053300-A1 Compositions Comprising A Near Terminal-Branched Compound And Methods Of Making The Same THE PROCTER & GAMBLE COMPANY 2013-02-28 US claimed
EP-2523652-A1 INTERMEDIATES AND SURFACTANTS USEFUL IN HOUSEHOLD CLEANING AND PERSONAL CARE COMPOSITIONS, AND METHODS OF MAKING THE SAME The Procter & Gamble Company (US) 2012-11-21 EP claimed
US-20120012130-A1 Method of Cleansing Hair THE PROCTER & GAMBLE COMPANY 2012-01-19 US claimed
WO-2012009539-A2 METHOD OF CLEANSING HAIR THE PROCTER & GAMBLE COMPANY (US) 2012-01-19 WO claimed
WO-2012009525-A2 COMPOSITIONS COMPRISING A NEAR TERMINAL-BRANCHED COMPOUND AND METHODS OF MAKING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2012-01-19 WO claimed
WO-2011088089-A1 INTERMEDIATES AND SURFACTANTS USEFUL IN HOUSEHOLD CLEANING AND PERSONAL CARE COMPOSITIONS, AND METHODS OF MAKING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2011-07-21 WO claimed
US-20110171155-A1 Intermediates And Surfactants useful In Household Cleaning And Personal Care Compositions, And Methods Of Making The Same THE PROCTER & GAMBLE COMPANY 2011-07-14 US claimed
CN-115551978-A Detergent compositions containing branched surfactants 宝洁公司 2022-12-30 CN disclosed
EP-3688150-A1 LIPASE VARIANTS AND MICROCAPSULE COMPOSITIONS COMPRISING SUCH LIPASE VARIANTS Novozymes A/S (DK) 2020-08-05 EP disclosed
EP-3619304-A1 COMPOSITIONS COMPRISING LIPASE AND SULFITE Novozymes A/S (DK) 2020-03-11 EP disclosed
US-20190169542-A1 LIQUID CLEANING COMPOSITIONS PROCTER & GAMBLE (US) 2019-06-06 US disclosed
EP-3485008-A1 LIPASE VARIANTS, POLYNUCLEOTIDES ENCODING SAME AND THE USE THEREOF Novozymes A/S (DK) 2019-05-22 EP disclosed
US-20120012130-A1 Method of Cleansing Hair THE PROCTER & GAMBLE COMPANY 2012-01-19 US disclosed
WO-2012009539-A2 METHOD OF CLEANSING HAIR THE PROCTER & GAMBLE COMPANY (US) 2012-01-19 WO disclosed
WO-2012009660-A2 DETERGENT COMPOSITIONS COMPRISING MICROBIALLY PRODUCED FATTY ALCOHOLS AND DERIVATIVES THEREOF THE PROCTER & GAMBLE COMPANY (US) 2012-01-19 WO disclosed
WO-2011088089-A1 INTERMEDIATES AND SURFACTANTS USEFUL IN HOUSEHOLD CLEANING AND PERSONAL CARE COMPOSITIONS, AND METHODS OF MAKING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2011-07-21 WO disclosed
US-20110171155-A1 Intermediates And Surfactants useful In Household Cleaning And Personal Care Compositions, And Methods Of Making The Same THE PROCTER & GAMBLE COMPANY 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120012130-A1 Method of Cleansing Hair POLR1C, SHH, LATS2 BLM 2440/4885KDM4E 1947/4885CA5A 2990/4885
US-20110171155-A1 Intermediates And Surfactants useful In Household Cleaning And Personal Care Compositions, And Methods Of Making The Same HACD2, DSG1, HACD3 BLM 348/4885KDM4E 3626/4885CA5A 2817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.