Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 16/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinmetacin SCHEMBL29974302 | 0.92 | LMNA (0.68) | PLA2G2APTGS2LMNACYP1A2CYP2D6 | |
| Cinmetacin SCHEMBL25139 | 0.92 | LMNA (0.68) | PLA2G2APTGS2LMNACYP1A2CYP2D6 | |
| Cinmetacin SCHEMBL25138 | 0.92 | LMNA (0.68) | PLA2G2APTGS2LMNACYP1A2CYP2D6 | |
| Cinmetacin SCHEMBL8636225 | 0.91 | LMNA (0.67) | PLA2G2APTGS2LMNACYP1A2CYP2D6 | |
| SCHEMBL12609001 | 0.91 | LMNA (0.58) | PLA2G2APTGS2LMNACYP1A2CYP2D6 | |
| Cinmetacin SCHEMBL8636226 | 0.91 | LMNA (0.67) | PLA2G2APTGS2LMNACYP1A2CYP2D6 | |
| SCHEMBL12628642 | 0.90 | AKR1C3 (0.62) | PLA2G2APTGS2LMNACYP1A2CYP2D6 | |
| SCHEMBL13849829 | 0.89 | PTGS2 (0.61) | PLA2G2APTGS2LMNACYP1A2CYP2D6 | |
| SCHEMBL9815439 | 0.88 | LMNA (0.53) | PLA2G2APTGS2LMNACYP1A2CYP2D6 | |
| SCHEMBL9815440 | 0.88 | LMNA (0.53) | PLA2G2APTGS2LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009124371-A9 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2010-12-02 | — | — | WO | claimed |
| WO-2009124371-A2 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2009-10-15 | — | — | WO | claimed |