Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.68 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.63 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.63 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.59 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.59 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinmetacin SCHEMBL25138 | 1.00 | LMNA (0.68) | LMNACYP1A2CYP2C9HIF1ANPSR1 | |
| Cinmetacin SCHEMBL25139 | 1.00 | LMNA (0.68) | LMNACYP1A2CYP2C9HIF1ANPSR1 | |
| Cinmetacin SCHEMBL8636226 | 0.99 | LMNA (0.67) | LMNACYP1A2CYP2C9HIF1ANPSR1 | |
| Cinmetacin SCHEMBL8636225 | 0.99 | LMNA (0.67) | LMNACYP1A2CYP2C9HIF1ANPSR1 | |
| SCHEMBL12609001 | 0.93 | LMNA (0.58) | LMNACYP1A2CYP2C9HIF1ANPSR1 | |
| SCHEMBL3459041 | 0.92 | PLA2G2A (0.69) | LMNACYP1A2CYP2C9HIF1ANPSR1 | |
| SCHEMBL12628642 | 0.92 | AKR1C3 (0.62) | LMNACYP1A2CYP2C9HIF1ANPSR1 | |
| SCHEMBL13849829 | 0.91 | PTGS2 (0.61) | LMNACYP1A2CYP2C9HIF1ANPSR1 | |
| SCHEMBL9815440 | 0.89 | LMNA (0.53) | LMNACYP1A2CYP2C9HIF1ANPSR1 | |
| SCHEMBL9815439 | 0.89 | LMNA (0.53) | LMNACYP1A2CYP2C9HIF1ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015601-A | Methods and compositions for ADAR-mediated SERPINA1 editing | 科罗生物公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-115175667-A | Lipid vesicle composition with permeation enhancer | 迪迪艾斯研究公司 | 2022-10-11 | — | — | CN | disclosed |