SCHEMBL3460112

SCHEMBL3460112

OB(O)c1cc(O)ccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 5/20 0.44
LMNA P02545 4/20 0.44
ALOX15 P16050 4/20 0.44
CYP2C9 P11712 3/20 0.44
TYR P14679 2/20 0.44
HTT P42858 2/20 0.44
NR1I2 O75469 1/20 0.44
MIF P14174 1/20 0.44
NFE2L2 Q16236 1/20 0.44
MAOB P27338 1/20 0.44
ENPP2 Q13822 2/20 0.42
PTGS1 P23219 1/20 0.40
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
ALOX5 P09917 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3791077 0.81 MAOB (0.48) ALDH1A1HSD17B10LMNAALOX15CYP2C9
SCHEMBL30381231 0.79 TYR (0.42) ALDH1A1HSD17B10LMNAALOX15CYP2C9
SCHEMBL3791591 0.79 TYR (0.42) ALDH1A1HSD17B10LMNAALOX15CYP2C9
SCHEMBL16295806 0.77 ACHE (0.46) ALDH1A1ALOX15HTTENPP2HPGD
SCHEMBL29953635 0.77 TRPA1 (0.56) ALDH1A1HSD17B10LMNAALOX15HTT
SCHEMBL2823017 0.77 TRPA1 (0.56) ALDH1A1HSD17B10LMNAALOX15HTT
SCHEMBL16426121 0.77 ENPP2 (0.46) ALDH1A1ENPP2CA1CA2KDM4E
SCHEMBL262997 0.75 HSD17B10 (0.54) ALDH1A1HSD17B10ALOX15ENPP2CA12
SCHEMBL7772653 0.75 CA3 (0.46) ALDH1A1HSD17B10LMNAPTGS1CA1
SCHEMBL3791253 0.75 CA14 (0.43) ALDH1A1HSD17B10LMNAALOX15CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117886790-A Synthesis method of CochlearolB 陕西师范大学 2024-04-16 CN claimed
CN-117886790-B CochlearolB synthesis method 陕西师范大学 2025-10-28 CN disclosed
CN-117886790-A Synthesis method of CochlearolB 陕西师范大学 2024-04-16 CN disclosed
CN-117886790-A Synthesis method of CochlearolB 陕西师范大学 2024-04-16 CN disclosed
EP-3730590-A1 LIQUID CRYSTAL MEDIA WITH HOMEOTROPIC ALIGNMENT Merck Patent GmbH (DE) 2020-10-28 EP disclosed
EP-2918658-B1 Liquid crystalline media with homeotropic alignment MERCK PATENT GMBH (DE) 2020-05-13 EP disclosed
US-10513657-B2 Liquid-crystalline media having homeotropic alignment MERCK PATENT GMBH (DE) 2019-12-24 US disclosed
US-20180057743-A1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2018-03-01 US disclosed
US-9809748-B2 Liquid-crystalline media having homeotropic alignment MERCK PATENT GMBH (DE) 2017-11-07 US disclosed
EP-2918658-A2 Liquid crystalline media with homeotropic alignment Merck Patent GmbH (DE) 2015-09-16 EP disclosed
US-20150252265-A1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2015-09-10 US disclosed
EP-2240016-A1 AMPK MODULATORS Mercury Therapeutics, Inc. (US) 2010-10-20 EP disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
WO-2009100130-A1 AMPK MODULATORS MERCURY THERAPEUTICS, INC. (US) 2009-08-13 WO disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed
US-5346801-A Boron anion salt of cationic dye as photoinitiator KONICA CORPORATION (JP) 1994-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 ALDH1A1 4339/4885HSD17B10 1100/4885LMNA 3250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.