Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL3461238

CCCCCCCCCCCCCCCCc1c(Cl)ncc(C)c1C.N

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMP P19971 3/20 0.36
MAPT P10636 3/20 0.35
RAB9A P51151 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
STAT3 P40763 1/20 0.35
ATM Q13315 1/20 0.35
KCNH2 Q12809 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TYR P14679 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
CCR5 P51681 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4453790 0.76 TYMP (0.41) TYMPMAPTRAB9ASMN1; SMN2NPC1
SCHEMBL27672334 0.74 NOS2 (0.47) TYMPMAPTRAB9ASMN1; SMN2NPC1
SCHEMBL28052887 0.74 NOS2 (0.47) TYMPMAPTRAB9ASMN1; SMN2NPC1
SCHEMBL3322337 0.74 TYMP (0.39) TYMPMAPTRAB9ASMN1; SMN2NPC1
SCHEMBL24113990 0.70 KMT2A (0.43) TYMPKCNH2ALDH1A1HPGDKMT2A
SCHEMBL29143502 0.69 TYMP (0.39) TYMPSMN1; SMN2ATMKCNH2ALDH1A1
SCHEMBL14394420 0.69 TYMP (0.36) TYMPMAPTRAB9ASMN1; SMN2NPC1
SCHEMBL29487433 0.67 TYR (0.44) KCNH2ALDH1A1KDM4EHSD17B10TYR
SCHEMBL5933485 0.67 TYR (0.44) KCNH2ALDH1A1KDM4EHSD17B10TYR
SCHEMBL12495916 0.67 ALDH1A1 (0.39) TYMPRAB9ASMN1; SMN2NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010067245-A1 BIOSURFACTANT COMPOSITION PRODUCED BY A NEW BACILLUS LICHENIFORMIS STRAIN, USES AND PRODUCTS THEREOF PAN-ECO S.A. (LU) 2010-06-17 WO disclosed
US-20100015245-A1 Combination of Copper Cations with Peroxides or Quaternary Ammonium Compounds for the Treatment of Biofilms UTI LIMITED PARTNERSHIP (CA) 2010-01-21 US disclosed
WO-2009130608-A2 COMBINATION OF COPPER CATIONS WITH PEROXIDES OR QUATERNARY AMMONIUM COMPOUNDS FOR THE TREATMENT OF BIOFILMS UTI LIMITED PARTNERSHIP (CA) 2009-10-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100015245-A1 Combination of Copper Cations with Peroxides or Quaternary Ammonium Compounds for the Treatment of Biofilms AOC1, AOC2, SOD1 TYMP 4733/4885MAPT 4169/4885RAB9A 2875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.