Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7624194 | 0.84 | CASP1 (0.68) | CASP1ALDH1A1CYP3A4MAPT | |
| SCHEMBL7396978 | 0.82 | CA12 (0.57) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7434407 | 0.79 | GAA (0.60) | ALDH1A1MAPTTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL4557754 | 0.78 | GAA (0.63) | CASP1ALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL7647656 | 0.76 | TGM2 (0.52) | ALDH1A1TGM2SMN1; SMN2KMT2A | |
| SCHEMBL11002529 | 0.75 | CASP1 (0.49) | CASP1ALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL28300827 | 0.75 | SMN1; SMN2 (0.48) | CASP1ALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL17895893 | 0.74 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRHSD17B10TGM2 | |
| SCHEMBL473103 | 0.74 | TDP1 (0.55) | ALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL14560262 | 0.74 | CASP1 (0.54) | CASP1ALDH1A1CYP3A4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |