SCHEMBL346477

SCHEMBL346477

C=C(C)C(=O)OCCOP(=O)(O)OCCBr

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.38
BTN3A1 O00481 1/20 0.38
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromoethane SCHEMBL3220997 0.92 THRB (0.53) THRBTSHRALDH1A1BTN3A1POLB
SCHEMBL31091982 0.91 THRB (0.55) THRBTSHRALDH1A1BTN3A1POLB
SCHEMBL15194 0.91 THRB (0.55) THRBTSHRALDH1A1BTN3A1POLB
SCHEMBL27997825 0.91 THRB (0.41) THRBTSHRALDH1A1BTN3A1
Ammonia Solution, Strong SCHEMBL18140715 0.90 THRB (0.53) THRBTSHRALDH1A1BTN3A1POLB
Phosphoric Acid SCHEMBL11307097 0.90 THRB (0.53) THRBTSHRALDH1A1BTN3A1POLB
SCHEMBL6833450 0.86 THRB (0.50) THRBTSHRALDH1A1BTN3A1POLB
SCHEMBL2638796 0.86 THRB (0.59) THRBTSHRALDH1A1BTN3A1POLB
SCHEMBL6833452 0.86 THRB (0.50) THRBTSHRALDH1A1BTN3A1POLB
SCHEMBL4797967 0.86 THRB (0.59) THRBTSHRALDH1A1BTN3A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3039309-A None JP disclosed
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT SHOFU INC. (JP) 2024-05-30 US disclosed
CN-111743783-B Double-paste type dental resin reinforced glass ion water-gate composition 株式会社松风 2024-04-16 CN disclosed
CN-112545901-B One-part dental adhesive composition 株式会社松风 2024-03-22 CN disclosed
EP-3047839-B1 FILLER TREATED WITH AN ACIDIC POLYMER SHOFU INC (JP) 2024-03-13 EP disclosed
EP-4321145-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT Shofu Inc. (JP) 2024-02-14 EP disclosed
EP-3604318-B1 PHOSPHORUS-CONTAINING COMPOUND MITSUI CHEMICALS INC (JP) 2024-01-17 EP disclosed
US-20230414465-A1 POWDER MIXTURE FOR SPRAYING INTO TOOTH SURFACE OR INTO GINGIVAL SULCUS/PERIODONTAL POCKET KABUSHIKI KAISHA SHOFU (JP) 2023-12-28 US disclosed
EP-4260912-A1 POWDER MIXTURE FOR SPRAYING INTO TOOTH SURFACE OR INTO GINGIVAL SULCUS/PERIODONTAL POCKET Kabushiki Kaisha Shofu (JP) 2023-10-18 EP disclosed
US-11786444-B2 Dental polyfunctional monomers and dental hydroxyl group-containing monomers MITSUI CHEMICALS, INC. (JP) 2023-10-17 US disclosed
US-6620861-B1 Fine particles covered with polysiloxane KABUSHIKI KAISHA SHOFU (JP) 2003-09-16 US disclosed
US-20030083398-A1 Dental composition kit KURARAY CO. LTD. (JP) 2003-05-01 US disclosed
US-20030055123-A1 Dental cement composition KURARAY CO. LTD, (JP) 2003-03-20 US disclosed
EP-0821931-B1 Metal fluoride particles and a dental composition including said metal fluoride particles KURARAY CO (JP) 2003-01-15 EP disclosed
EP-1269968-A1 Dental cement composition KURARAY CO., LTD. (JP) 2003-01-02 EP disclosed
EP-1269967-A1 Dental composition kit KURARAY CO., LTD. (JP) 2003-01-02 EP disclosed
EP-1101484-A2 Dental fillers KABUSHIKI KAISHA SHOFU (JP) 2001-05-23 EP disclosed
US-5908879-A A POLYSILOXANE COATING ON THE SURFACE OF THE PARTICLE. KURARAY CO., LTD. (JP) 1999-06-01 US disclosed
EP-0821931-A2 Metal fluoride particles and a dental composition including said metal fluoride particles KURARAY CO., LTD. (JP) 1998-02-04 EP disclosed
JP-H0339309-A 2-METHACRYLOYLOXYETHYLPHOSPHORYLCHOLINE COPOLYMER RES DEV CORP OF JAPAN 1991-02-20 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11786444-B2 Dental polyfunctional monomers and dental hydroxyl group-containing monomers PAM, CAD, FHIT THRB 873/4885TSHR 2948/4885ALDH1A1 1173/4885
US-20230414465-A1 POWDER MIXTURE FOR SPRAYING INTO TOOTH SURFACE OR INTO GINGIVAL SULCUS/PERIODONTAL POCKET SP1, CROCC, CA3 THRB 2136/4885TSHR 2278/4885ALDH1A1 4314/4885
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT GRIK1, GRIN2B, GRIK2 THRB 599/4885TSHR 2655/4885ALDH1A1 1560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.