Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 8/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467198 | 0.84 | PPARA (0.47) | FFAR1FFAR4PPARDPPARGPPARA | |
| SCHEMBL3466993 | 0.83 | OTUD7B (0.38) | OTUD7BPPARDPPARGPPARADGAT1 | |
| SCHEMBL3466901 | 0.83 | PGR (0.41) | DGAT1 | |
| SCHEMBL3467451 | 0.81 | OTUD7B (0.41) | OTUD7BFFAR1PPARDPPARGPPARA | |
| SCHEMBL3308412 | 0.81 | KIF11 (0.53) | FFAR4PPARDPPARADGAT1 | |
| SCHEMBL3466408 | 0.81 | PGR (0.53) | — | |
| SCHEMBL3467479 | 0.80 | ALDH1A1 (0.38) | FFAR4DGAT1 | |
| SCHEMBL3467216 | 0.80 | PYGL (0.41) | FFAR1DGAT1MAOB | |
| SCHEMBL3710805 | 0.77 | HSD17B10 (0.49) | — | |
| SCHEMBL3467229 | 0.77 | FFAR1 (0.38) | FFAR1FFAR4DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074807-A1 | 3, 4-DIHYDROQUINOLIN-2 ( 1H ) -ONE DERIVATIVES AS SODIUM CHANNEL MODULATORS | GILEAD PALO ALTO, INC. (US) | 2010-07-01 | — | — | WO | disclosed |