Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 6/20 | 0.40 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466993 | 0.90 | OTUD7B (0.38) | OTUD7BPGRPPARDPPARGPPARA | |
| SCHEMBL3466408 | 0.87 | PGR (0.53) | PARP10PARP11PGRDCLRE1B | |
| SCHEMBL3467479 | 0.87 | ALDH1A1 (0.38) | PGRGRK6 | |
| SCHEMBL3467737 | 0.85 | TDP2 (0.46) | KDM4EDHODHPPARG | |
| SCHEMBL3468501 | 0.84 | TDP2 (0.44) | PGR | |
| SCHEMBL3467229 | 0.84 | FFAR1 (0.38) | PGRFFAR1 | |
| SCHEMBL3466901 | 0.83 | PGR (0.41) | PGRGSK3B | |
| SCHEMBL3308412 | 0.82 | KIF11 (0.53) | PPARDPPARACDK2 | |
| SCHEMBL3467216 | 0.82 | PYGL (0.41) | PGRFFAR1 | |
| SCHEMBL3466924 | 0.82 | KIF11 (0.41) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074807-A1 | 3, 4-DIHYDROQUINOLIN-2 ( 1H ) -ONE DERIVATIVES AS SODIUM CHANNEL MODULATORS | GILEAD PALO ALTO, INC. (US) | 2010-07-01 | — | — | WO | claimed |