Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | TERT | O14746 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436938 | 0.87 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTHTTTP53 | |
| SCHEMBL3467516 | 0.81 | L3MBTL1 (0.71) | ALDH1A1LMNAMAPTHTTTP53 | |
| SCHEMBL8779333 | 0.80 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTHTTTP53 | |
| SCHEMBL9277488 | 0.80 | NPC1 (0.47) | ALDH1A1LMNAMAPTHTTTP53 | |
| SCHEMBL13328499 | 0.77 | NPC1 (0.44) | ALDH1A1LMNAMAPTHTTTP53 | |
| SCHEMBL8779340 | 0.74 | CYP1A2 (0.77) | ALDH1A1LMNAMAPTHTTMEN1 | |
| SCHEMBL3263155 | 0.72 | LMNA (0.72) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9321665 | 0.72 | MEN1 (0.57) | ALDH1A1LMNAMAPTHTTTP53 | |
| SCHEMBL10999271 | 0.70 | MEN1 (0.57) | ALDH1A1LMNAMAPTHTTTP53 | |
| SCHEMBL13819917 | 0.69 | KMT2A (0.43) | ALDH1A1MAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992456-A | Plant protection | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| EP-0369234-A2 | 2,5-Disubstituted 1,3,4-thiadiazole derivatives, process for their preparation and their use as pesticides | BAYER AG (DE) | 1990-05-23 | — | — | EP | disclosed |