Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3472577 | 0.87 | OPRM1 (0.38) | CNR2KDM4ELMNAKMT2AGAA | |
| SCHEMBL3469163 | 0.74 | CASP3 (0.55) | KDM4EKMT2AGAAMEN1POLB | |
| SCHEMBL6947705 | 0.73 | GAA (0.62) | KDM4ELMNASMN1; SMN2KMT2AGAA | |
| SCHEMBL8307191 | 0.73 | GAA (0.61) | KDM4ELMNASMN1; SMN2KMT2AGAA | |
| SCHEMBL6949259 | 0.70 | GAA (0.53) | LMNASMN1; SMN2KMT2AGAAMEN1 | |
| SCHEMBL3471618 | 0.70 | ALOX5AP (0.49) | CNR2KDM4EKMT2AGAAMEN1 | |
| SCHEMBL3468579 | 0.69 | GAA (0.48) | CNR2KDM4EKMT2AGAAMEN1 | |
| SCHEMBL2782035 | 0.68 | KMT2A (0.56) | SMN1; SMN2KMT2AGAAMEN1POLB | |
| SCHEMBL3467433 | 0.67 | KMT2A (0.49) | CNR2KDM4EKMT2AGAAMEN1 | |
| SCHEMBL2762571 | 0.66 | KMT2A (0.41) | KDM4EKMT2AGAAMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077839-A1 | SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT | WYETH LLC (FORMERLY KNOWN AS WYETH) (US) | 2010-07-08 | — | — | WO | claimed |