Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886735 | 0.81 | ACHE (0.41) | TDP1PPARGPPARAMEN1KMT2A | |
| SCHEMBL28306045 | 0.79 | LTA4H (0.44) | TDP1MEN1KMT2AMAPTLMNA | |
| SCHEMBL8995789 | 0.79 | PPARA (0.40) | SLC6A4PPARGPPARAGAANPSR1 | |
| SCHEMBL8890078 | 0.79 | ALDH1A1 (0.40) | SLC6A4TDP1PPARGPPARAALDH1A1 | |
| SCHEMBL25331886 | 0.78 | SLC6A4 (0.39) | SLC6A4KDM4EPPARGPPARAALDH1A1 | |
| SCHEMBL3468664 | 0.78 | SLC6A4 (0.39) | SLC6A4KDM4EPPARGPPARAALDH1A1 | |
| SCHEMBL12953262 | 0.78 | LDHA (0.45) | LDHASLC6A4KDM4ETDP1MAPK1 | |
| SCHEMBL9966866 | 0.77 | LDHA (0.44) | LDHASLC6A4KDM4ETDP1MEN1 | |
| SCHEMBL28334987 | 0.77 | LDHA (0.44) | LDHASLC6A4KDM4ETDP1MEN1 | |
| SCHEMBL8887243 | 0.76 | MAPT (0.41) | KDM4ETDP1MAPK1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691340-A | CENTRAL NERVOUS SYSTEM DISORDERS, STROKES, CARDIOVASCULAR DISORDERS, ALZHEIMER*S DISEASE OR ANTIINFLAMMATORY AGENTS | ADIR ET COMPAGNIE (FR) | 1997-11-25 | — | — | US | disclosed |