Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878342 | 0.88 | ATXN2 (0.37) | TAS1R3TAS1R1TAS1R2JAK3ATXN2 | |
| SCHEMBL899603 | 0.78 | MAPT (0.50) | PLAUTPMTTDP1MEN1KMT2A | |
| SCHEMBL3469047 | 0.78 | KDM4C (0.42) | FFAR4ACACB | |
| SCHEMBL21314319 | 0.76 | ATXN2 (0.57) | JAK3ATXN2 | |
| SCHEMBL15662782 | 0.76 | KMT2A (0.45) | PLAUTDP1KMT2A | |
| SCHEMBL20202164 | 0.74 | GPR84 (0.47) | TDP1MEN1KMT2A | |
| SCHEMBL10287469 | 0.74 | PLA2G2A (0.49) | MEN1KMT2A | |
| SCHEMBL3714048 | 0.74 | TAS1R3 (0.40) | TAS1R3TAS1R1TAS1R2FFAR4PLAU | |
| SCHEMBL7875153 | 0.74 | BACE1 (0.45) | FFAR4 | |
| SCHEMBL7880559 | 0.74 | TACR3 (0.36) | TAS1R3TAS1R1TAS1R2ATXN2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |