Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.97 |
| ▸ | MEN1 | O00255 | 1/20 | 0.97 |
| ▸ | ABL1 | P00519 | 1/20 | 0.97 |
| ▸ | LMNA | P02545 | 1/20 | 0.97 |
| ▸ | PKM | P14618 | 1/20 | 0.97 |
| ▸ | IDE | P14735 | 1/20 | 0.97 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.97 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.97 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.97 |
| ▸ | HLCS | P50747 | 6/20 | 0.68 |
| ▸ | CA12 | O43570 | 7/20 | 0.55 |
| ▸ | CA1 | P00915 | 7/20 | 0.55 |
| ▸ | CA2 | P00918 | 7/20 | 0.55 |
| ▸ | CA9 | Q16790 | 7/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biotin SCHEMBL398483 | 1.00 | TDP1 (0.97) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL36572 | 0.99 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL410686 | 0.99 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL3384633 | 0.99 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL9841217 | 0.99 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL23055065 | 0.99 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL21981206 | 0.99 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL20547409 | 0.99 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL22943835 | 0.99 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL59420 | 0.99 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988004289-A1 | NON-RADIOACTIVE NUCLEIC ACID PROBES | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1988-06-16 | — | — | WO | claimed |
| US-20100048890-A1 | CONJUGATED SMALL MOLECULES | DISCOVERX CORPORATION | 2010-02-25 | — | — | US | disclosed |
| EP-1711825-A4 | CONJUGATED SMALL MOLECULES | AMBIT BIOSCIENCES CORP (US) | 2008-01-23 | — | — | EP | disclosed |
| US-7172877-B2 | Methods and compositions for peptide and protein labeling | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-02-06 | — | — | US | disclosed |
| EP-1711825-A2 | CONJUGATED SMALL MOLECULES | Ambit Biosciences Corporation (US) | 2006-10-18 | — | — | EP | disclosed |
| US-20050233389-A1 | Methods and compositions for peptide and protein labeling | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-10-20 | — | — | US | disclosed |
| WO-2005067644-A2 | CONJUGATED SMALL MOLECULES | AMBIT BIOSCIENCES CORPORATION (US) | 2005-07-28 | — | — | WO | disclosed |
| US-20050153371-A1 | Conjugated small molecules | AMBIT BIOSCIENCES CORPORATION | 2005-07-14 | — | — | US | disclosed |
| US-20040209317-A1 | Methods and compositions for peptide and protein labeling | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-10-21 | — | — | US | disclosed |
| US-5880270-A | USED IN IMMUNODIAGNOSTIC AND SEPARATION TECHNIQUES | CELLPRO, INCORPORATED (US) | 1999-03-09 | — | — | US | disclosed |
| US-5856571-A | Semicarbazide-containing linker compounds for formation of stably-linked conjugates and methods related thereto | CELLPRO, INCORPORATED (US) | 1999-01-05 | — | — | US | disclosed |
| WO-1996040263-A2 | SEMICARBAZIDE-CONTAINING LINKER COMPOUNDS FOR FORMATION OF STABLY-LINKED CONJUGATES AND METHODS RELATED THERETO | CELLPRO, INCORPORATED (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996040662-A2 | AMINOOXY-CONTAINING LINKER COMPOUNDS AND THEIR APPLICATION IN CONJUGATES | CELLPRO, INCORPORATED (US) | 1996-12-19 | — | — | WO | disclosed |
| US-4775745-A | Diazonium compounds useful as components for nucleic acid probes | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1988-10-04 | — | — | US | disclosed |
| WO-1988004289-A1 | NON-RADIOACTIVE NUCLEIC ACID PROBES | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1988-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048890-A1 | CONJUGATED SMALL MOLECULES | ERBB2, ALK, ACP1 | TDP1 3880/4885MEN1 4141/4885ABL1 12/4885 |
| US-20050233389-A1 | Methods and compositions for peptide and protein labeling | HLCS, BTD, QPCTL | TDP1 3223/4885MEN1 1564/4885ABL1 2145/4885 |
| US-20050153371-A1 | Conjugated small molecules | ERBB2, ALK, ACP1 | TDP1 3880/4885MEN1 4141/4885ABL1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.