Biotin

Biotin

SCHEMBL398483

N.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.97
MEN1 O00255 1/20 0.97
ABL1 P00519 1/20 0.97
LMNA P02545 1/20 0.97
PKM P14618 1/20 0.97
IDE P14735 1/20 0.97
MAPK1 P28482 1/20 0.97
KMT2A Q03164 1/20 0.97
RIN1 Q13671 1/20 0.97
L3MBTL1 Q9Y468 1/20 0.97
HLCS P50747 6/20 0.68
CA12 O43570 7/20 0.55
CA1 P00915 7/20 0.55
CA2 P00918 7/20 0.55
CA9 Q16790 7/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL3473268 1.00 TDP1 (0.97) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL36572 0.99 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL410686 0.99 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL3384633 0.99 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL9841217 0.99 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL23055065 0.99 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL21981206 0.99 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL20547409 0.99 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL22943835 0.99 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL59420 0.99 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110819614-B Method for improving driving force of enzyme-driven micro-nano motor 武汉理工大学 2023-04-11 CN claimed
CN-110438074-A A kind of immunocyte recovery culture solution and preparation method thereof GUANGZHOU SHAAI BIOLOGICAL TECH CO LTD 2019-11-12 CN claimed
CN-106967213-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2017-07-21 CN claimed
US-20060222588-A1 Antilymphoma targeting agents with effector and affinity functions linked by a trifunctional reagent GLYCOREX TRANSPLANTATION AB (SE) 2006-10-05 US claimed
US-20050191682-A1 Methods for fragmenting DNA AFFYMETRIX, INC. (US) 2005-09-01 US claimed
EP-1564306-A2 Methods for fragmenting and labeling DNA Affymetrix, Inc. (US) 2005-08-17 EP claimed
US-20250353886-A1 Modification and Compositions of Human Secretoglobin Proteins APC RES ASSETS LLC (US) 2025-11-20 US disclosed
US-20250339542-A1 CONVERSION OF A BIOLOGICALLY SILENT MIRNA BINDING SMALL MOLECULE TO AN MIRNA DEGRADER UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-11-06 US disclosed
WO-2025054616-A1 PLATFORM APPROACH F-18 RADIOLABELING OF VARIOUS PEPTIDES IN AQUEOUS MEDIUM MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2025-03-13 WO disclosed
US-20240239818-A1 COMPOUNDS AND COMPOSITIONS COMPRISING FLUOROPHORES FOR USE IN VISUALIZATION AND PURIFICATION OR MANIPULATION HOWARD HUGHES MEDICAL INSTITUTE 2024-07-18 US disclosed
CN-111065417-B Immunogenic compositions 美商艾芬尼维克斯公司 2024-04-19 CN disclosed
EP-4327876-A2 IMMUNOGENIC COMPOSITIONS Affinivax, Inc. (US) 2024-02-28 EP disclosed
US-20230414740-A1 IMMUNOGENIC COMPOSITIONS AFFINIVAX, INC. 2023-12-28 US disclosed
US-5976535-A ADMINISTERING A FIRST CONJUGATE COMPRISING A TARGETING MOIETY AND STREPTAVIDIN; AND SUBSEQUENTLY ADMINISTERING A SECOND CONJUGATE COMPRISING A CYTOKINE AND BIOTIN, REDUCING THE ENDOGENOUS BIOTIN LEVEL NEORX CORPORATION (US) 1999-11-02 US disclosed
EP-0733066-A4 PRETARGETING METHODS AND COMPOUNDS NEORX CORP (US) 1999-04-21 EP disclosed
WO-1998021521-A1 TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-05-22 WO disclosed
EP-0733066-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1996-09-25 EP disclosed
WO-1995015979-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-15 WO disclosed
EP-0526587-A1 MODIFICATION OF POLYMER SURFACES BY TREATMENT WITH Ce(IV) SALTS AND ELECTROMAGNETIC RADIATION NOVO NORDISK A/S (DK) 1993-02-10 EP disclosed
WO-1991016377-A1 MODIFICATION OF POLYMER SURFACES BY TREATMENT WITH Ce(IV) SALTS AND ELECTROMAGNETIC RADIATION NOVO NORDISK A/S (DK) 1991-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239818-A1 COMPOUNDS AND COMPOSITIONS COMPRISING FLUOROPHORES FOR USE IN VISUALIZATION AND PURIFICATION OR MANIPULATION STAMBP, MSN, SYPL1 TDP1 2926/4885MEN1 3796/4885ABL1 1651/4885
US-20250339542-A1 CONVERSION OF A BIOLOGICALLY SILENT MIRNA BINDING SMALL MOLECULE TO AN MIRNA DEGRADER NSUN3, AGO2, ZFR TDP1 1666/4885MEN1 1716/4885ABL1 4245/4885
US-20060222588-A1 Antilymphoma targeting agents with effector and affinity functions linked by a trifunctional reagent CD47, CD40, TNFSF11 TDP1 2602/4885MEN1 798/4885ABL1 791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.