SCHEMBL3473376

SCHEMBL3473376

NC(=O)c1ccccc1C(=O)NSC(Cl)(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.42
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 3/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
METAP2 P50579 1/20 0.39
SIRT1 Q96EB6 1/20 0.39
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
CTNNB1 P35222 1/20 0.35
SIRT2 Q8IXJ6 1/20 0.35
IRAK4 Q9NWZ3 1/20 0.34
CA1 P00915 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL459549 0.87 KDM4E (0.39) BCAT2KDM4EALDH1A1MAPTHPGD
SCHEMBL11011223 0.80 SIRT1 (0.48) BCAT2KDM4EALDH1A1MAPTHPGD
SCHEMBL6306644 0.80 KDM4E (0.48) BCAT2KDM4EALDH1A1MAPTHPGD
SCHEMBL10741701 0.77 KDM4E (0.45) BCAT2KDM4EALDH1A1MAPTHPGD
SCHEMBL4121945 0.74 KDM4E (0.50) BCAT2KDM4EALDH1A1MAPTHPGD
SCHEMBL17766647 0.73 ALDH1A1 (0.54) BCAT2KDM4EALDH1A1MAPTHPGD
SCHEMBL28544441 0.72 MEN1 (0.43) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL29666482 0.72 MEN1 (0.43) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL4967588 0.72 ALDH1A1 (0.70) BCAT2KDM4EALDH1A1MAPTHPGD
SCHEMBL39118 0.72 ALDH1A1 (0.70) BCAT2KDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4516862-A1 AQUEOUS COATING COMPOSITION, COATING OBTAINED FROM THE COATING COMPOSITION, SUBSTRATE CONTAINING THE COATING AND THE USE OF THE AQUEOUS COATING COMPOSITION DAW SE (DE) 2025-03-05 EP claimed
EP-2667718-B1 COMPOSITION COMPRISING AN ELICITOR OF THE PLANT IMMUNE SYSTEM FYTOFEND S A (BE) 2016-03-30 EP claimed
EP-4516862-A1 AQUEOUS COATING COMPOSITION, COATING OBTAINED FROM THE COATING COMPOSITION, SUBSTRATE CONTAINING THE COATING AND THE USE OF THE AQUEOUS COATING COMPOSITION DAW SE (DE) 2025-03-05 EP disclosed
EP-1697446-B1 METHOD OF TREATING A PLASTIC ARTICLE BAYER MATERIALSCIENCE LLC (US) 2015-08-19 EP disclosed
US-8524796-B2 Active polymer compositions DOW GLOBAL TECHNOLOGIES LLC 2013-09-03 US disclosed
CN-101408002-B Method of tinting a plastic article BAYER MATERIALSCIENCE LLC 2013-04-10 CN disclosed
US-20100041292-A1 ACTIVE POLYMER COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2010-02-18 US disclosed
CN-100503962-C Method of dyeing a plastic article BAYER MATERIALSCIENCE AG (US) 2009-06-24 CN disclosed
EP-2050866-A2 Method of tinting a plastic article Bayer MaterialScience LLC (US) 2009-04-22 EP disclosed
CN-101408002-A Method of tinting a plastic article BAYER MATERIALSCIENCE LLC (US) 2009-04-15 CN disclosed
US-20090089942-A1 Method of tinting a plastic article BAYER MATERIALSCIENCE LLC 2009-04-09 US disclosed
US-5718793-A EJECTING INK DROPS CONTAINING DISPERSE DYE TO FORM IMAGE ON PRINTING SHEET, CONTACTING SHEET WITH HEATING WITH BASE MATERIAL HAVING RECEIVING LAYER, SEPARATING; RECEIVING LAYER EXHIBITS IMPROVED HARDNESS CANON KABUSHIKI KAISHA (JP) 1998-02-17 US disclosed
CN-1020904-C Agricultural compositions containing fungicidal carbinols DU PONT (US) 1993-05-26 CN disclosed
CN-1070908-A The preparation method of agricultural combination containing antifungal carbinols DU PONT MERCK PHARMA (US) 1993-04-14 CN disclosed
US-4708960-A N-(arylpropyl)-azolylureas, and fungicides containing these compounds BASF AKTIENGESELLSCHAFT (DE) 1987-11-24 US disclosed
US-4686239-A WITHIN PORES OF THERMOPLASTIC POWDER; MORTON THIOKOL, INC. (US) 1987-08-11 US disclosed
US-4663359-A POROUS THERMOPLASTIC, NON-DUSTING MORTON THIOKOL, INC. (US) 1987-05-05 US disclosed
US-4661528-A HIGH CONCENTRATION, POROUS THERMOPLASTIC POWDER, NON-DUSTING AND FREE-FLOWING MORTON THIOKOL, INC. (US) 1987-04-28 US disclosed
EP-0197631-A2 Dry blend concentrate of solid biocide and thermoplastic resin powder and method for its preparation MORTON INTERNATIONAL, INC. (US) 1986-10-15 EP disclosed
US-4086297-A MELT BLENDING WITH MICROBIOCIDE TO EFFECT IMMOBILIZATION VENTRON CORPORATION (US) 1978-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041292-A1 ACTIVE POLYMER COMPOSITIONS MSN, MMAB, FGB BCAT2 4739/4885KDM4E 2470/4885ALDH1A1 4366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.