Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11011223 | 0.88 | SIRT1 (0.48) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL28968036 | 0.86 | BCAT2 (0.53) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL17766647 | 0.80 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL3473376 | 0.80 | BCAT2 (0.42) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL39118 | 0.79 | ALDH1A1 (0.70) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL4967588 | 0.79 | ALDH1A1 (0.70) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL27700719 | 0.79 | ALDH1A1 (0.70) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL1520940 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29872360 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL4138337 | 0.78 | CTSD (0.55) | KDM4EALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6943268-B2 | Method for induction of L-selectin shedding | SCIENCE & TECHNOLOGY CORPORATION @ UNM (US) | 2005-09-13 | — | — | US | disclosed |
| US-20030092763-A1 | Method for induction of L-selectin shedding | SCIENCE & TECHNOLOGY CORPORATION @UNM | 2003-05-15 | — | — | US | disclosed |
| US-6498189-B1 | SUPPRESSION OF INFLAMMATION AND OF LYMPH NODE ENTRY BY CALMODULIN ANTAGONISTS; CELL ASSOCIATED PROTEIN DISULFIDE ISOMERASE INHIBITORS; P-AMINOPHENYLARSINE OXIDES | UNIVERSITY OF NEW MEXICO | 2002-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092763-A1 | Method for induction of L-selectin shedding | PDIA5, PDIA4, PDIA6 | KDM4E 3839/4885ALDH1A1 1261/4885MAPT 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.