Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.55 |
| ▸ | DHODH | Q02127 | 4/20 | 0.52 |
| ▸ | FABP1 | P07148 | 1/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CTRC | Q99895 | 2/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3474997 | 0.93 | DHODH (0.54) | LDHADHODHFABP1P2RY14CYP3A4 | |
| SCHEMBL1495762 | 0.89 | LDHA (0.50) | LDHADHODHCYP3A4CYP2A6CTRC | |
| SCHEMBL3063243 | 0.87 | P2RX3 (0.44) | LDHADHODHCYP3A4CYP2A6CTRC | |
| SCHEMBL24365554 | 0.86 | LDHA (0.56) | LDHADHODHCYP3A4CYP2A6KMO | |
| SCHEMBL31145138 | 0.86 | LDHA (0.56) | LDHADHODHCYP3A4CYP2A6KMO | |
| SCHEMBL3476171 | 0.84 | DHODH (0.49) | LDHADHODHCYP3A4CYP2A6CTRC | |
| SCHEMBL2480995 | 0.82 | CYP3A4 (0.56) | LDHACYP3A4CYP2A6KMOCCR1 | |
| SCHEMBL2171200 | 0.82 | RAB9A (0.44) | LDHACYP3A4CYP2A6CTRCCCR1 | |
| SCHEMBL358035 | 0.82 | LDHA (0.58) | LDHADHODHCYP3A4CYP2A6CTRC | |
| SCHEMBL409583 | 0.82 | LDHA (0.44) | LDHACYP3A4CYP2A6CTRCCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133122-B2 | Amide compounds, compositions and uses thereof | EVOTEC AG (DE) | 2015-09-15 | — | — | US | disclosed |
| US-20140323532-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2014-10-30 | — | — | US | disclosed |
| WO-2010033168-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323532-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | IL1B, ADORA2B, AVPR1B | LDHA 208/4885DHODH 3626/4885FABP1 1608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.