Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317817 | 1.00 | ALOX15 (0.43) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL3474110 | 0.79 | ALDH1A1 (0.42) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL14536877 | 0.78 | ALOX15 (0.60) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL197189 | 0.76 | ALOX15 (0.52) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL14999140 | 0.76 | GLO1 (0.44) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9653474 | 0.76 | ALOX15 (0.43) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL3158392 | 0.76 | ALOX15 (0.43) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9653470 | 0.76 | ALOX15 (0.43) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL3158398 | 0.76 | ALOX15 (0.43) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL20456805 | 0.74 | GLO1 (0.38) | GLO1ALDH1A1LMNAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050106689-A1 | Synthesis of aminocrotonates | SOLVAY FLUOR UND DERIVATE GMBH (DE) | 2005-05-19 | — | — | US | disclosed |