Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094589 | 0.87 | SCN9A (0.49) | SCN9A | |
| SCHEMBL28556096 | 0.80 | SCN9A (0.39) | SCN9A | |
| SCHEMBL29736477 | 0.80 | SCN9A (0.39) | SCN9A | |
| SCHEMBL3478009 | 0.76 | SCN9A (0.49) | SCN9A | |
| SCHEMBL20528519 | 0.75 | SCN9A (0.38) | SCN9AKDM4E | |
| SCHEMBL1093593 | 0.74 | SCN9A (0.40) | SCN9AKDM4E | |
| SCHEMBL29736437 | 0.74 | SCN9A (0.40) | SCN9AKDM4E | |
| SCHEMBL3475862 | 0.74 | SCN9A (0.45) | SCN9A | |
| SCHEMBL20586166 | 0.73 | KDM4E (0.42) | SCN9AKDM4E | |
| SCHEMBL1094007 | 0.73 | SCN9A (0.48) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197655-A1 | SULFONAMIDE DERIVATIVES | Pfizer Limited Icagen, Inc. | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197655-A1 | SULFONAMIDE DERIVATIVES | SULT2A1, SULT1A1, TPST2 | SCN9A 73/4885KDM4E 4039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.