SCHEMBL3476847

SCHEMBL3476847

CCO[Si](OCC)(OCC)C(C)CCNC(=O)OC

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.43
KCNA5 P22460 1/20 0.35
CHRNB2 P17787 4/20 0.35
CHRNB4 P30926 4/20 0.35
CHRNA4 P43681 4/20 0.35
CHRNA3 P32297 3/20 0.35
LMNA P02545 1/20 0.32
ACHE P22303 5/20 0.32
MAPT P10636 1/20 0.31
HRH4 Q9H3N8 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
KMT2A Q03164 2/20 0.30
TSHR P16473 1/20 0.30
GLA P06280 1/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
NR1H4 Q96RI1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544298 0.86 CYP2D6 (0.36) CHRNB2CHRNB4CHRNA4CHRNA3LMNA
SCHEMBL3144816 0.84 CHRNB2 (0.31) CHRNB2CHRNB4CHRNA4CHRNA3
SCHEMBL3478212 0.83 EPHX1 (0.42) EPHX1KCNA5CHRNB2CHRNB4CHRNA4
SCHEMBL2261531 0.77
SCHEMBL5949707 0.74 EPHX1 (0.48) EPHX1KCNA5LMNAGAA
SCHEMBL20616625 0.73 EPHX1 (0.48) EPHX1KCNA5CHRNB2CHRNB4CHRNA4
SCHEMBL5916829 0.73 EPHX1 (0.48) EPHX1ACHEKMT2ATSHRGLA
SCHEMBL3464049 0.73 CYP2C19 (0.32) KMT2ATSHRGLAMEN1
SCHEMBL3910038 0.73 GABRP (0.31)
SCHEMBL22495750 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937697-B1 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-16 EP claimed
US-7825243-B2 Process for the production of isocyanatosilane and silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-11-02 US claimed
EP-1869058-B1 PROCESS FOR MAKING SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-12-16 EP claimed
CN-101268087-A Method for production of isocyanatosilanes MOMENTIVE PERFORMANCE MAT INC (US) 2008-09-17 CN claimed
EP-1937697-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES Momentive Performance Materials Inc. (US) 2008-07-02 EP claimed
EP-1869058-A2 PROCESS FOR MAKING SILYLISOCYANURATE General Electric Company (US) 2007-12-26 EP claimed
WO-2007037817-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-04-05 WO claimed
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate GENERAL ELECTRIC COMPANY 2006-12-07 US claimed
WO-2006113182-A2 PROCESS FOR MAKING SILYLISOCYANURATE GENERAL ELECTRIC COMPANY (US) 2006-10-26 WO claimed
US-20060235221-A1 Process for making silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. 2006-10-19 US claimed
US-7060849-B1 Method for production of isocyanatosilanes GENERAL ELECTRIC COMPANY (US) 2006-06-13 US claimed
US-7825243-B2 Process for the production of isocyanatosilane and silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-11-02 US disclosed
EP-1869058-B1 PROCESS FOR MAKING SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-12-16 EP disclosed
EP-1885731-B1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-11-11 EP disclosed
EP-1885731-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE Momentive Performance Materials Inc. (US) 2008-02-13 EP disclosed
EP-1869058-A2 PROCESS FOR MAKING SILYLISOCYANURATE General Electric Company (US) 2007-12-26 EP disclosed
WO-2006132799-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2006-12-14 WO disclosed
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate GENERAL ELECTRIC COMPANY 2006-12-07 US disclosed
WO-2006113182-A2 PROCESS FOR MAKING SILYLISOCYANURATE GENERAL ELECTRIC COMPANY (US) 2006-10-26 WO disclosed
US-20060235221-A1 Process for making silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235221-A1 Process for making silylisocyanurate PCMT1, SRM, STOM EPHX1 4442/4885KCNA5 1839/4885CHRNB2 4568/4885
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate SI, TST, PCMT1 EPHX1 4685/4885KCNA5 2164/4885CHRNB2 4596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.