Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1994684 | 0.76 | CRHBP (0.63) | CRHBPCRHR2GAA | |
| Hydrochloric Acid SCHEMBL9247859 | 0.74 | CRHBP (0.61) | CRHBPCRHR2GAA | |
| Trifluoroacetic Acid SCHEMBL9251412 | 0.73 | CRHBP (0.49) | CRHBPCRHR2 | |
| Nitric Acid SCHEMBL8647053 | 0.71 | CRHBP (0.57) | CRHBPCRHR2GAA | |
| SCHEMBL1997904 | 0.71 | ESR1 (0.33) | CRHBPCRHR2 | |
| SCHEMBL7248680 | 0.67 | GAA (0.33) | CRHBPCRHR2GAA | |
| SCHEMBL9921596 | 0.67 | GAA (0.38) | CRHBPCRHR2GAA | |
| SCHEMBL436830 | 0.67 | GAA (0.33) | CRHBPCRHR2GAA | |
| SCHEMBL3739463 | 0.66 | CRHBP (0.34) | CRHBPCRHR2 | |
| SCHEMBL25475858 | 0.66 | CRHBP (0.50) | CRHBPCRHR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250049756-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | NORTHROP GRUMMAN SYSTEMS CORP (US) | 2025-02-13 | — | — | US | disclosed |
| US-11925617-B2 | Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof | NORTHROP GRUMMAN SYSTEMS (US) | 2024-03-12 | — | — | US | disclosed |
| US-20220016077-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | NORTHROP GRUMMAN INNOVATION SYSTEMS LLC | 2022-01-20 | — | — | US | disclosed |
| US-20200046682-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | NORTHROP GRUMMAN SYSTEMS CORPORATION | 2020-02-13 | — | — | US | disclosed |
| US-20180085346-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | Northrop Grumman Innovation Systems, Inc. | 2018-03-29 | — | — | US | disclosed |
| US-20160199346-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | NORTHROP GRUMMAN SYSTEMS CORPORATION | 2016-07-14 | — | — | US | disclosed |
| US-20150246020-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | NORTHROP GRUMMAN SYSTEMS CORPORATION | 2015-09-03 | — | — | US | disclosed |
| US-20130123216-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | ALLIANT TECHSYSTEMS INC. (US) | 2013-05-16 | — | — | US | disclosed |
| US-7745643-B2 | chemical synthesizing a N-(haloacetyl)-3,3-dinitro-azetidine compound; anticarciogenic, antiinflammatory, antihypoxic, antidiabetic agent; cardiovascular and autoimmune disease; rheumatoid arthritis, diabetic retinopathy | ALLIANT TECHSYSTEMS INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-20090163466-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | RADIORX, INC. (US) | 2009-06-25 | — | — | US | disclosed |
| US-20090093644-A1 | METHODS OF SYNTHESIZING CYCLIC NITRO COMPOUNDS | ALLIANT TECHSYSTEMS INC. (US) | 2009-04-09 | — | — | US | disclosed |
| EP-1924253-A2 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | ATK Thiokol Propulsion Inc. (US) | 2008-05-28 | — | — | EP | disclosed |
| US-20070135384-A1 | Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof | RADIORX, INC. (US) | 2007-06-14 | — | — | US | disclosed |
| WO-2007022225-A2 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | ATK THIOKOL PROPULSION INC. (US) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123216-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | NOS1, NOS2, NOS3 | CRHBP 4430/4885CRHR2 3865/4885GAA 3166/4885 |
| US-20160199346-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | NOS1, NOS2, NOS3 | CRHBP 4430/4885CRHR2 3865/4885GAA 3166/4885 |
| US-20150246020-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | NOS1, NOS2, NOS3 | CRHBP 4430/4885CRHR2 3865/4885GAA 3166/4885 |
| US-20200046682-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | NOS1, NOS2, NOS3 | CRHBP 4430/4885CRHR2 3865/4885GAA 3166/4885 |
| US-20090093644-A1 | METHODS OF SYNTHESIZING CYCLIC NITRO COMPOUNDS | NOS2, NOS1, NOS3 | CRHBP 4205/4885CRHR2 3653/4885GAA 3578/4885 |
| US-20180085346-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | NOS1, NOS2, NOS3 | CRHBP 4430/4885CRHR2 3865/4885GAA 3166/4885 |
| US-20220016077-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | NOS1, NOS2, NOS3 | CRHBP 4430/4885CRHR2 3865/4885GAA 3166/4885 |
| US-20070135384-A1 | Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof | NOS1, NOS2, NOS3 | CRHBP 4430/4885CRHR2 3865/4885GAA 3166/4885 |
| US-11925617-B2 | Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof | NOS1, NOS2, NOS3 | CRHBP 4430/4885CRHR2 3865/4885GAA 3166/4885 |
| US-20090163466-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | NOS1, NOS2, NOS3 | CRHBP 4430/4885CRHR2 3865/4885GAA 3166/4885 |
| US-20250049756-A1 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | NOS1, NOS2, NOS3 | CRHBP 4430/4885CRHR2 3865/4885GAA 3166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.