Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5824341 | 0.84 | OPRM1 (0.47) | OPRM1TRPM8TRPA1KCNA5P2RX4 | |
| SCHEMBL2392586 | 0.82 | OPRM1 (0.45) | OPRM1TRPM8TRPA1KCNA5P2RX4 | |
| SCHEMBL10700915 | 0.81 | KCNA5 (0.50) | OPRM1TRPM8TRPA1KCNA5P2RX4 | |
| SCHEMBL4638544 | 0.81 | OPRM1 (0.45) | OPRM1TRPM8TRPA1KCNA5P2RX4 | |
| SCHEMBL9698663 | 0.80 | OPRM1 (0.50) | OPRM1TRPM8TRPA1KCNA5P2RX4 | |
| SCHEMBL9873557 | 0.77 | OPRM1 (0.41) | OPRM1TRPM8TRPA1KCNA5P2RX4 | |
| SCHEMBL8498802 | 0.76 | KCNA5 (0.46) | OPRM1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL31546067 | 0.76 | OPRM1 (0.58) | OPRM1TRPM8TRPA1KCNA5P2RX4 | |
| SCHEMBL8336802 | 0.75 | KCNA5 (0.44) | OPRM1TRPM8TRPA1KCNA5P2RX4 | |
| SCHEMBL9558707 | 0.75 | KCNA5 (0.44) | OPRM1TRPM8TRPA1KCNA5P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10426752-B2 | Menthol-derivative compounds and use thereof as oral and systemic active agents | COLGATE-PALMOLIVE COMPANY (US) | 2019-10-01 | — | — | US | disclosed |
| US-20120014884-A1 | MENTHOL-DERIVATIVE COMPOUNDS AND USE THEREOF AS ORAL AND SYSTEMIC ACTIVE AGENTS | COLGATE-PALMOLIVE COMPANY (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10426752-B2 | Menthol-derivative compounds and use thereof as oral and systemic active agents | CD14, SMAD2, ARG1 | OPRM1 452/4885TRPM8 213/4885TRPA1 369/4885 |
| US-20120014884-A1 | MENTHOL-DERIVATIVE COMPOUNDS AND USE THEREOF AS ORAL AND SYSTEMIC ACTIVE AGENTS | CD14, SMAD2, ARG1 | OPRM1 452/4885TRPM8 213/4885TRPA1 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.