SCHEMBL3481490

SCHEMBL3481490

CC(C[SiH2]Cl)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.52
AOC3 Q16853 2/20 0.47
TRPA1 O75762 5/20 0.45
RIPK1 Q13546 1/20 0.45
HTR2A P28223 1/20 0.41
HRH1 P35367 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GFER P55789 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9092727 0.80 ADRB2 (0.46) AOC3TDP1TSHR
SCHEMBL705505 0.78 HTR2A (0.46) TAAR1HTR2AHRH1TDP1TSHR
SCHEMBL3482033 0.77 TAAR1 (0.52) TAAR1AOC3TRPA1RIPK1KDM4E
SCHEMBL11651391 0.77 TAAR1 (0.52) TAAR1AOC3TRPA1RIPK1
SCHEMBL29403357 0.76 TAAR1 (0.50) TAAR1AOC3TRPA1RIPK1HTR2A
SCHEMBL5266627 0.76 TAAR1 (0.50) TAAR1AOC3TRPA1RIPK1KDM4E
SCHEMBL2736711 0.73 TAAR1 (0.58) TAAR1AOC3TRPA1RIPK1HTR2A
SCHEMBL6583604 0.73 TAAR1 (0.58) TAAR1AOC3TRPA1RIPK1HTR2A
SCHEMBL9092685 0.72 ADRB2 (0.43) AOC3TDP1TSHRKDM4EALDH1A1
SCHEMBL6280516 0.72 RIPK1 (0.67) TAAR1AOC3TRPA1RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2128897-B1 SILICON DIELECTRIC TREATING AGENT FOR USE AFTER ETCHING, PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJITSU LTD (JP) 2015-05-06 EP disclosed
US-8716209-B2 Agent for post-etch treatment of silicon dielectric film, method of manufacturing semiconductor device, and semiconductor device FUJITSU LIMITED (JP) 2014-05-06 US disclosed
US-20100007031-A1 AGENT FOR POST-ETCH TREATMENT OF SILICON DIELECTRIC FILM, METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2010-01-14 US disclosed
EP-2128897-A1 SILICON DIELECTRIC TREATING AGENT FOR USE AFTER ETCHING, PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE Fujitsu Limited (JP) 2009-12-02 EP disclosed
US-7427692-B2 Process for preparation of 7-[α-amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid LUPIN LTD. (US) 2008-09-23 US disclosed
US-7230097-B2 Process for preparation of 7-[α-Amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid LUPIN LTD. (IN) 2007-06-12 US disclosed
US-20060149096-A1 Process for preparation of 7-[a-amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid LUPIN LTD. (IN) 2006-07-06 US disclosed
US-20050113570-A1 Process for preparation of 7-[alpha-amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid LUPIN LTD. (IN) 2005-05-26 US disclosed
US-4504657-A Cephadroxil monohydrate BRISTOL-MYERS COMPANY (US) 1985-03-12 US disclosed
US-RE31730-E Process for the preparation of the crystalline monohydrate of 7-(D-α-aα-(p-hydroxyphenyl)acetamido)-3-methyl-3-cephem-4-carboxylic acid BRISTOL-MYERS COMPANY (US) 1984-11-13 US disclosed
US-4291160-A 7-(1,3-Dithiolan-2-imino)-Δ2 -cephalosporanic acid derivatives RICHARDSON-MERRELL INC. (US) 1981-09-22 US disclosed
US-4234721-A Process for the preparation of the crystalline monohydrate of 7-[D-amino-(p-hydroxyphenyl]acetamido)-3-methyl-3-cephen-4-carboxylic acid BRISTOL-MYERS COMPANY (US) 1980-11-18 US disclosed
US-4208516-A 7-(1,3-Dithiolan-2-imino)-Δ2 -cephalosporanic acid derivatives RICHARDSON-MERRELL INC. (US) 1980-06-17 US disclosed
US-4206305-A FROM S-ALKYLATED SALT OF 1,3-DITHIOLANE-2-THIONE AND A 7-AMINOCEPHALOSPORANIC ACID, BACTERICIDES RICHARDSON-MERRELL INC. (US) 1980-06-03 US disclosed
US-4206119-A ANTIBIOTICS, BACTERICIDES RICHARDSON-MERRELL INC. (US) 1980-06-03 US disclosed
US-4160863-A ANTIBIOTIC BRISTOL-MYERS COMPANY (US) 1979-07-10 US disclosed
US-4066657-A ANTIBACTERIAL AGENTS FOR ANIMAL FEED SUPPLEMENTS PFIZER INC. (US) 1978-01-03 US disclosed
US-4036846-A ANTIBACTERIAL PFIZER INC. (US) 1977-07-19 US disclosed
US-4031077-A Antibacterial 3-phosphono penams PFIZER INC. (US) 1977-06-21 US disclosed
US-3994939-A BACTERICIDES PFIZER INC. (US) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113570-A1 Process for preparation of 7-[alpha-amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid IGLV6-57, APC, HBZ TAAR1 4529/4885AOC3 1292/4885TRPA1 4753/4885
US-20060149096-A1 Process for preparation of 7-[a-amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid IGLV6-57, APC, IL2 TAAR1 4517/4885AOC3 1393/4885TRPA1 4753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.