SCHEMBL3481832

SCHEMBL3481832

O=C(c1ccncc1)c1cc(Cl)ccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 2/20 0.59
JAK1 P23458 2/20 0.59
TYK2 P29597 2/20 0.59
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
RAB9A P51151 2/20 0.58
POLB P06746 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.54
ALDH1A1 P00352 3/20 0.53
TP53 P04637 1/20 0.53
CCR9 P51686 5/20 0.51
NPC1 O15118 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
SRD5A2 P31213 1/20 0.47
KCNMA1 Q12791 2/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10084176 0.86 RAB9A (0.50) JAK2JAK1TYK2MEN1KMT2A
SCHEMBL7466437 0.85 ALDH1A1 (0.61) MEN1KMT2ARAB9APOLBALDH1A1
SCHEMBL14419512 0.84 KCNMA1 (0.60) JAK2JAK1TYK2MEN1KMT2A
SCHEMBL31366630 0.83 RECQL (0.57) MEN1KMT2ARAB9APOLBSMN1; SMN2
SCHEMBL28060 0.83 RECQL (0.57) MEN1KMT2ARAB9APOLBSMN1; SMN2
SCHEMBL230930 0.81 ALDH1A1 (0.63) MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1
SCHEMBL29612638 0.81 ALDH1A1 (0.63) MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1
SCHEMBL2169680 0.81 KDM4E (0.53) JAK2JAK1TYK2MEN1KMT2A
SCHEMBL15906641 0.81 CCR9 (0.64) SMN1; SMN2ALDH1A1CCR9KCNMA1LMNA
SCHEMBL8160214 0.80 ALDH1A1 (0.71) JAK2JAK1TYK2RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8729219-B2 Polyarylene block copolymer having sulfonic acid group and use thereof JSR CORPORATION (JP) 2014-05-20 US disclosed
US-8729219-B2 Polyarylene block copolymer having sulfonic acid group and use thereof JSR CORPORATION (JP) 2014-05-20 US disclosed
US-20130085236-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF JSR CORPORATION (JP) 2013-04-04 US disclosed
US-20130085236-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF JSR CORPORATION (JP) 2013-04-04 US disclosed
US-8273499-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-09-25 US disclosed
US-8273499-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-09-25 US disclosed
US-8273499-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-09-25 US disclosed
US-20120052412-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF HONDA MOTOR CO., LTD. (JP) 2012-03-01 US disclosed
US-20120052412-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF HONDA MOTOR CO., LTD. (JP) 2012-03-01 US disclosed
US-20100062311-A1 MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2010-03-11 US disclosed
US-20100062311-A1 MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2010-03-11 US disclosed
US-20100062311-A1 MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2010-03-11 US disclosed