SCHEMBL3481929

SCHEMBL3481929

O=S(=O)(c1cccnc1)c1cc(Cl)ccc1Cl

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.63
NAMPT P43490 2/20 0.55
ALPL P05186 4/20 0.51
LMNA P02545 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
PKM P14618 1/20 0.48
CYP2C19 P33261 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
GAA P10253 1/20 0.47
POLB P06746 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
NFE2L2 Q16236 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
RXFP1 Q9HBX9 1/20 0.44
AKR1B1 P15121 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7974619 0.81 AKR1B1 (0.47) ALDH1A1NAMPTLMNACYP3A4GAA
SCHEMBL228959 0.80 KIF18A (0.57) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL13309929 0.77 KIF18A (0.58) ALDH1A1NAMPTCYP3A4CYP2C9CYP2C19
SCHEMBL3937548 0.77 NAPRT (0.52) ALDH1A1NAMPTALPLLMNACYP3A4
SCHEMBL9475478 0.76 ALDH1A1 (0.60) ALDH1A1NAMPTCYP3A4POLBAKR1B1
SCHEMBL5068459 0.75 MCL1 (0.57) ALDH1A1LMNAPKMGAAAKR1B1
SCHEMBL9232776 0.75 NAPRT (0.68) ALDH1A1NAMPTCYP1A2CYP3A4NAPRT
SCHEMBL31404866 0.75 NAPRT (0.68) ALDH1A1NAMPTCYP1A2CYP3A4NAPRT
SCHEMBL16479407 0.75 POLB (0.53) ALDH1A1NAMPTALPLLMNAPOLB
Pyridine SCHEMBL6114845 0.74 ALDH1A1 (0.51) ALDH1A1NAMPTLMNAGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273499-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-09-25 US disclosed
US-8273499-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-09-25 US disclosed
US-8273499-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-09-25 US disclosed
US-20100062311-A1 MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2010-03-11 US disclosed
US-20100062311-A1 MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2010-03-11 US disclosed
US-20100062311-A1 MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2010-03-11 US disclosed