Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3481929 | 0.81 | ALDH1A1 (0.63) | AKR1B1ALDH1A1LMNANAMPTGAA | |
| SCHEMBL7974641 | 0.79 | ALDH1A1 (0.61) | AKR1B1ALDH1A1LMNANAMPTHPGD | |
| SCHEMBL9475478 | 0.78 | ALDH1A1 (0.60) | AKR1B1ALDH1A1NAMPTMCL1TSHR | |
| SCHEMBL5068459 | 0.78 | MCL1 (0.57) | AKR1B1ALDH1A1LMNAMCL1GAA | |
| SCHEMBL228959 | 0.75 | KIF18A (0.57) | AKR1B1ALDH1A1MCL1GAATSHR | |
| SCHEMBL7971906 | 0.74 | HTR6 (0.52) | ALDH1A1LMNANAMPTL3MBTL1CYP3A4 | |
| SCHEMBL12696990 | 0.72 | POLB (0.54) | AKR1B1ALDH1A1MCL1GAATSHR | |
| SCHEMBL1533667 | 0.72 | PTGDR2 (0.49) | AKR1B1ALDH1A1MCL1GAATSHR | |
| SCHEMBL13309929 | 0.72 | KIF18A (0.58) | AKR1B1ALDH1A1NAMPTMCL1TSHR | |
| SCHEMBL10656611 | 0.72 | MEN1 (0.63) | AKR1B1ALDH1A1LMNAMCL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |