SCHEMBL3482786

SCHEMBL3482786

C[Si](C)(C)Oc1cc(I)c(O[Si](C)(C)C)cc1I

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.31
HTR2C P28335 3/20 0.31
HTR1A P08908 2/20 0.31
HTR2B P41595 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
PMP22 Q01453 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15134982 0.91 HTR2A (0.43) HTR2AHTR2CHTR1AHTR2BCYP1A2
SCHEMBL15134989 0.78 THRA (0.42) HTR2BCYP3A4LMNA
SCHEMBL8545516 0.76
SCHEMBL12758265 0.69 NQO2 (0.32) LMNA
SCHEMBL481337 0.67 HTR2A (0.54) HTR2AHTR2CHTR1AHTR2BCYP1A2
SCHEMBL6703730 0.65 CA1 (0.45) HTR2AHTR2CHTR2BTSHRLMNA
SCHEMBL8832605 0.63 LMNA (0.38) HTR2AHTR2CHTR2BTSHRNFKB1
SCHEMBL9517612 0.63 ALDH1A1 (0.39)
SCHEMBL16433700 0.62
SCHEMBL13318427 0.62 ALDH1A1 (0.43) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121647-B1 ORGANIC THIN FILM TRANSISTORS COMPRISING THIENYL OLIGOMERS AND THEIR USE AS GASEOUS PHASE SENSORS UNIV BARI (IT) 2014-09-24 EP disclosed
US-8461354-B2 Organic thin film transistors comprising thienyl oligomers and their use as gaseous phase sensors UNIVERSITA' DEGLI STUDI DI BARI (IT) 2013-06-11 US disclosed
US-8461354-B2 Organic thin film transistors comprising thienyl oligomers and their use as gaseous phase sensors UNIVERSITA' DEGLI STUDI DI BARI (IT) 2013-06-11 US disclosed
US-20100140597-A1 Organic thin film transistors comprising thienyl oligomers and their use as gaseous phase sensors UNIVERSITA' DEGLI STUDI DI BARI (IT) 2010-06-10 US disclosed
US-20100140597-A1 Organic thin film transistors comprising thienyl oligomers and their use as gaseous phase sensors UNIVERSITA' DEGLI STUDI DI BARI (IT) 2010-06-10 US disclosed
EP-2121647-A1 ORGANIC THIN FILM TRANSISTORS COMPRISING THIENYL OLIGOMERS AND THEIR USE AS GASEOUS PHASE SENSORS Universita' Degli Studi di Bari (IT) 2009-11-25 EP disclosed
WO-2008096239-A1 ORGANIC THIN FILM TRANSISTORS COMPRISING THIENYL OLIGOMERS AND THEIR USE AS GASEOUS PHASE SENSORS UNIVERSITA' DEGLI STUDI DI BARI (IT) 2008-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100140597-A1 Organic thin film transistors comprising thienyl oligomers and their use as gaseous phase sensors TPR, TTR, TRPA1 HTR2A 509/4885HTR2C 1220/4885HTR1A 356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.