Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3483021 | 0.91 | MC4R (0.46) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3482581 | 0.86 | ME2 (0.46) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL3482900 | 0.84 | KMT2A (0.52) | POLBMEN1KMT2AMAPTLMNA | |
| SCHEMBL11557311 | 0.80 | POLB (0.66) | POLBMEN1KMT2AENPP2MAPT | |
| SCHEMBL2114419 | 0.77 | ADRB1 (0.57) | POLBMAPTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL3482959 | 0.76 | AOC3 (0.43) | MAPTMC4RTP53 | |
| SCHEMBL3482923 | 0.75 | TP53 (0.50) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3482937 | 0.73 | KMT2A (0.50) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL12005574 | 0.73 | POLB (1.00) | POLBMEN1KMT2AENPP2MAPT | |
| SCHEMBL3482899 | 0.73 | CCR3 (0.57) | KMT2AMAPTALDH1A1HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150550-A1 | NOVEL CARBAMOYLOXY ARYL ALKAN ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND | SK Holdings Co., Ltd. (KR) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008140197-A1 | NOVEL CARBAMOYLOXY ARYL ALKAN ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND | SK HOLDINGS CO., LTD. (KR) | 2008-11-20 | — | — | WO | disclosed |